User profiles for C. Guillonneau

Carole Guillonneau

INSERM
Verified email at univ-nantes.fr
Cited by 2729

Immunoregulatory properties of the cytokine IL-34

C Guillonneau, S Bézie, I Anegon - Cellular and Molecular Life Sciences, 2017 - Springer
… IL-34 has been reported highly expressed in serum of chronically Hepatitis C (HCV)-infected
patients and correlating with fibrosis [83]. IL-34 differentiates monocytes into profibrogenic …

Future prospects for CD8+ regulatory T cells in immune tolerance

…, S Bézie, I Anegon, C Guillonneau - Immunological …, 2019 - Wiley Online Library
… Increase in CD8 + FOXP3 + Tregs along with CD4 + FOXP3 + Tregs was also observed in
patients with hepatitis C virus-induced vasculitis 106 and type 1 diabetic patients 107 treated …

[HTML][HTML] Super-Treg: toward a new era of adoptive Treg therapy enabled by genetic modifications

…, HD Volk, S Bézie, P Reinke, C Guillonneau… - Frontiers in …, 2021 - frontiersin.org
Regulatory Tcells (Treg) are essential components of peripheral immune homeostasis.
Adoptive Treg cell therapy has shown efficacy in a variety of immune-mediated diseases in …

[HTML][HTML] CD40Ig treatment results in allograft acceptance mediated by CD8+CD45RClow T cells, IFN-γ, and indoleamine 2,3-dioxygenase

C Guillonneau, M Hill, FX Hubert… - The Journal of …, 2007 - Am Soc Clin Investig
Treatment with CD40Ig results in indefinite allograft survival in a complete MHC-mismatched
heart allograft model in the rat. Here we show that serial second, third, and fourth adoptive …

Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity

C Guillonneau, JD Mintern, FX Hubert… - Proceedings of the …, 2009 - National Acad Sciences
Current influenza A virus vaccines do not generate significant immunity against serologically
distinct influenza A virus subtypes and would thus be ineffective in the face of a pandemic …

[HTML][HTML] IL-34 is a Treg-specific cytokine and mediates transplant tolerance

…, K Renaudin, I Anegon, C Guillonneau - The Journal of …, 2015 - Am Soc Clin Investig
… Thermal conditions were as follows: 3 seconds at 95C, 30 seconds at 60C, and 15 seconds
at –5C of the melting temperature with a final melting curve stage. The oligonucleotides used …

Mechanism and localization of CD8 regulatory T cells in a heart transplant model of tolerance

…, M Heslan, C Usal, L Liang, C Guillonneau… - The Journal of …, 2010 - journals.aai.org
… + Tregs in splenectomized recipients with long-surviving grafts, cell adoptive transfer
experiments and flow cytometry experiments were performed in other lymphoid organs or BM (C, D)…

Donor-specific allograft tolerance by administration of recipient-derived immature dendritic cells and suboptimal immunosuppression

G Bériou, H Pêche, C Guillonneau, E Merieau… - …, 2005 - journals.lww.com
We recently showed that injection of recipient-type immature bone marrow-derived dendritic
cells (iBMDCs) the day before transplantation induced a significant prolongation of allograft …

Fms-like tyrosine kinase 3 ligand recruits plasmacytoid dendritic cells to the brain

…, C Barcia, C Liu, FX Hubert, C Guillonneau… - The Journal of …, 2006 - journals.aai.org
… The cells were resuspended in 100 μl of cell surface staining buffer containing the
combinations of Abs described below and incubated for 30 min at 4C. After this incubation, the …

[HTML][HTML] Ex Vivo Expanded Human Non-Cytotoxic CD8+CD45RClow/− Tregs Efficiently Delay Skin Graft Rejection and GVHD in Humanized Mice

…, F Duteille, L David, I Anegon, C Guillonneau - Frontiers in …, 2018 - frontiersin.org
Both CD4 + and CD8 + Tregs play a critical role in the control of immune responses and
immune tolerance; however, our understanding of CD8 + Tregs is limited while they are …