DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis

…, HP Ellis, KM Kurian, AF Okuducu, C Jungk… - The lancet …, 2017 - thelancet.com
Background The WHO classification of brain tumours describes 15 subtypes of meningioma.
Nine of these subtypes are allotted to WHO grade I, and three each to grade II and grade III. …

[HTML][HTML] Evidence and consensus based guideline for the management of delirium, analgesia, and sedation in intensive care medicine. Revision 2015 (DAS …

…, J Horter, R Huth, U Janssens, C Jungk… - GMS German Medical …, 2015 - ncbi.nlm.nih.gov
In 2010, under the guidance of the DGAI (German Society of Anaesthesiology and Intensive
Care Medicine) and DIVI (German Interdisciplinary Association for Intensive Care and …

Novel, improved grading system (s) for IDH-mutant astrocytic gliomas

…, A Golanov, P Sinn, M Platten, C Jungk… - Acta …, 2018 - Springer
… : CDKN2A/B is not homozygously deleted, C+: high CNV-load, C−: low CNV-load. Parameter
… 3c). Model CNVL performed better in predicting OS of the groups than the 2016 CNS WHO …

Integrated molecular-morphologic meningioma classification: a multicenter retrospective analysis, retrospectively and prospectively validated

…, J Golfinos, C Sen, C Mawrin, C Jungk… - Journal of clinical …, 2021 - ascopubs.org
PURPOSE Meningiomas are the most frequent primary intracranial tumors. Patient outcome
varies widely from benign to highly aggressive, ultimately fatal courses. Reliable …

Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets

…, C Mawrin, U Schüller, C Jungk… - Acta …, 2016 - Springer
… Although C>T conversion artifacts by FFPE processing have mainly been reported in
amplicon-based and are rare in enrichment panels [10, 11, 32], we tested for those artifacts by …

Low-grade glioma surgery in intraoperative magnetic resonance imaging: results of a multicenter retrospective assessment of the German study group for …

…, A Pala, R König, L Bullinger, G Nagel, C Jungk… - …, 2016 - journals.lww.com
BACKGROUND: The ideal treatment strategy for low-grade gliomas (LGGs) is a
controversial topic. Additionally, only smaller single-center series dealing with the concept of …

[HTML][HTML] Tumor infiltration in enhancing and non-enhancing parts of glioblastoma: a correlation with histopathology

…, S Burth, JO Neumann, PJ Kieslich, F Sahm, C Jungk… - PloS one, 2017 - journals.plos.org
C) Calculated biopsy point C with its coordinates in an axial slide of the intraoperative cT1
MRI of an 82-year-old patient with glioblastoma. It lies in the CE area. D) Corresponding slice …

Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain

…, AK Nied, D Capper, B Brors, C Jungk… - Acta …, 2015 - Springer
c, d Show representative stainings for a LTS and STS case, respectively. CD cluster of … c
The left contingency table provides a numerical representation for the highly significant (p < 10 −…

Life after surgical resection of a meningioma: a prospective cross-sectional study evaluating health-related quality of life

…, K Au, MD Cusimano, MD Jenkinson, C Jungk… - Neuro …, 2019 - academic.oup.com
Background Few studies have evaluated the health-related quality of life (HRQoL) of
patients with meningiomas. Here, we report the largest prospective, longitudinal cross-sectional …

[HTML][HTML] Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients

C Jungk, D Chatziaslanidou, R Ahmadi, D Capper… - BMC cancer, 2016 - Springer
… more pronounced in patients with other therapies than BCNU at tumor recurrence (“with”
compared to “w/o” (without); b) as well as in patients with hypermethylated MGMT promoter (c) …