Mitochondria, Ca2+ and neurodegenerative disease

C Krieger, MR Duchen - European journal of pharmacology, 2002 - Elsevier
Mitochondria play a central role in cell biology not only as producers of ATP, but also in the
sequestration of Ca 2+ and the generation of free radicals. They are also repositories of …

Saccharomyces Genome Database: the genomics resource of budding yeast

…, BC Hitz, K Karra, CJ Krieger… - Nucleic acids …, 2012 - academic.oup.com
The Saccharomyces Genome Database (SGD, http://www.yeastgenome.org ) is the community
resource for the budding yeast Saccharomyces cerevisiae. The SGD project provides the …

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life

B Ajami, JL Bennett, C Krieger, W Tetzlaff… - Nature …, 2007 - nature.com
Microgliosis is a common response to multiple types of damage in the CNS. However, the
origin of the cells involved in this process is still controversial and the relative importance of …

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

B Ajami, JL Bennett, C Krieger, KM McNagny… - Nature …, 2011 - nature.com
… /vol) in 0.1 M PBS at 20–24 C. The spinal cord was removed and the tissue was post-fixed
for 24 h in 4% paraformaldehyde at 4 C and then cryoprotected in a 24% sucrose solution (wt/…

New CAST limit on the axion-photon interaction

…, N Kralj, M Krcmar, S Kostoglou, C Krieger… - arXiv preprint arXiv …, 2017 - arxiv.org
During 2003--2015, the CERN Axion Solar Telescope (CAST) has searched for $a\to\gamma$
conversion in the 9 T magnetic field of a refurbished LHC test magnet that can be directed …

[HTML][HTML] Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote

…, JM Cherry, NA Stover, CJ Krieger, C Del Toro… - PLoS …, 2006 - journals.plos.org
The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology.
Like other ciliates, this species has separate germline and soma functions that are …

[HTML][HTML] The essential deployment metamodel: a systematic review of deployment automation technologies

…, U Breitenbücher, M Falkenthal, C Krieger… - SICS Software-Intensive …, 2020 - Springer
In recent years, a plethora of deployment technologies evolved, many following a declarative
approach to automate the delivery of software components. Even if such technologies …

[PDF][PDF] TIA1 mutations in amyotrophic lateral sclerosis and frontotemporal dementia promote phase separation and alter stress granule dynamics

…, T Mittag, J Temirov, GYR Hsiung, C Krieger… - Neuron, 2017 - cell.com
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are age-related
neurodegenerative disorders with shared genetic etiologies and overlapping clinical and …

[HTML][HTML] The neuroinflammatory response in ALS: the roles of microglia and T cells

CA Lewis, J Manning, F Rossi, C Krieger - Neurology research …, 2012 - hindawi.com
… Correspondence should be addressed to Charles Krieger, ckrieger@sfu.ca … Krieger, “Mislocalization
of TDP43 in the G93A mutant SOD1 transgenic mouse model of ALS,” …

Conceptual design of the international axion observatory (IAXO)

…, M Krčmar, K Kousouris, C Krieger… - Journal of …, 2014 - iopscience.iop.org
The International Axion Observatory (IAXO) will be a forth generation axion helioscope. As
its primary physics goal, IAXO will look for axions or axion-like particles (ALPs) originating in …