[HTML][HTML] Microglial implication in Parkinson's disease: loss of beneficial physiological roles or gain of inflammatory functions?
C Lecours, M Bordeleau, L Cantin, M Parent… - Frontiers in Cellular …, 2018 - frontiersin.org
Microglia, often described as the brain-resident macrophages, play crucial roles in central
nervous system development, maintenance, plasticity, and adaptation to the environment. …
nervous system development, maintenance, plasticity, and adaptation to the environment. …
[HTML][HTML] From the Cajal alumni Achúcarro and Río-Hortega to the rediscovery of never-resting microglia
MÈ Tremblay, C Lecours, L Samson… - Frontiers in …, 2015 - frontiersin.org
… Río-Hortega continued the work of Achucarro and in 1919 developed his silver carbonate
method, finally enabling him to resolve microglia (C) from what he initially called interfascicular …
method, finally enabling him to resolve microglia (C) from what he initially called interfascicular …
Dark microglia: a new phenotype predominantly associated with pathological states
… The animals were housed under a 12-h light–dark cycle at 22C–25C with free access to …
Briefly, the sections were blocked and incubated overnight at 4 C in primary antibody solution, …
Briefly, the sections were blocked and incubated overnight at 4 C in primary antibody solution, …
Fractalkine receptor deficiency impairs microglial and neuronal responsiveness to chronic stress
… All samples were kept on ice and later centrifuged at 3000 rpm for 15 min at 4 C. Blood
plasma was transferred to Eppendorf tubes for corticosterone determination and stored at −80 C …
plasma was transferred to Eppendorf tubes for corticosterone determination and stored at −80 C …
miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo
…, F Jolivette, C Lecours, K Bisht, C Goupil… - Human molecular …, 2015 - academic.oup.com
… 2C and D), consistent with our previous observations (40). Tau mRNA remained unchanged
… 3A and C). This effect was specific for endogenous mouse tau, as human tau remained …
… 3A and C). This effect was specific for endogenous mouse tau, as human tau remained …
[HTML][HTML] Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain
…, A Aubert, V De Smedt-Peyrusse, C Lecours… - Nature …, 2020 - nature.com
Omega-3 fatty acids (n-3 PUFAs) are essential for the functional maturation of the brain.
Westernization of dietary habits in both developed and developing countries is accompanied by …
Westernization of dietary habits in both developed and developing countries is accompanied by …
Freestyle pedicle perforator flaps: clinical results and vascular anatomy
C Lecours, M Saint-Cyr, C Wong… - Plastic and …, 2010 - journals.lww.com
Background: Perforator flaps have increased in use, with advantages such as sparing of the
underlying muscle with resultant decreased donor-site morbidity and the possibility of …
underlying muscle with resultant decreased donor-site morbidity and the possibility of …
Fluoxetine treatment affects the inflammatory response and microglial function according to the quality of the living environment
…, S Garofalo, G Milior, H El Hajj, C Lecours… - Brain, behavior, and …, 2016 - Elsevier
… were: 95 C 10 min and 95 C 15 s, 60 C 1 min for 40 cycles. Single PCR products were
subjected to a heat dissociation (gradual increase of temperature from 60 C to 95 C) and agarose …
subjected to a heat dissociation (gradual increase of temperature from 60 C to 95 C) and agarose …
[HTML][HTML] Remodeling of lipid bodies by docosahexaenoic acid in activated microglial cells
Background Organelle remodeling processes are evolutionarily conserved and involved in
cell functions during development, aging, and cell death. Some endogenous and exogenous …
cell functions during development, aging, and cell death. Some endogenous and exogenous …
[HTML][HTML] Chronic stress exposure alters the gut barrier: sex-specific effects on microbiota and jejunum tight junctions
…, M Lavoie, JJ Leclerc, T Lecomte, C Lecours… - … Psychiatry Global Open …, 2024 - Elsevier
… (C) Chart describing the jejunum tight junction features and parameters analyzed. (D) t-SNE
visualization of the k-means clustering. The 4 features (ruffle quantity, width, fragmentation, …
visualization of the k-means clustering. The 4 features (ruffle quantity, width, fragmentation, …