Metabolic effects of a chronic dietary exposure to a low-dose pesticide cocktail in mice: sexual dimorphism and role of the constitutive androstane receptor

…, EL Jamin, JF Martin, C Naylies, C Canlet… - Environmental …, 2018 - ehp.niehs.nih.gov
… from 110C to 220C at a rate of 2 C / min , and the carrier gas was hydrogen [7.25 pounds
per square inch (psi)]. Injector and detector temperatures were 225C and 245C, respectively. …

[HTML][HTML] Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity

…, E Fouché, F Lasserre, C Naylies, C Bétoulières… - Scientific reports, 2020 - nature.com
… The amplification conditions were as follows: 95 C for 15 min, followed by 35 cycles of 94
C for 1 min, 65 C for 1 min, and 72 C for 1 min, and a final cycle of 72 C for 10 min. This …

[HTML][HTML] Deciphering the anti-aflatoxinogenic properties of eugenol using a large-scale q-PCR approach

I Caceres, R El Khoury, Á Medina, Y Lippi, C Naylies… - Toxins, 2016 - mdpi.com
… Ángel Medina contributed to the RNA extraction protocol and culture condition techniques;
Yannick Lippi and Claire Naylies contributed to q-PCR performance and data analysis. …

Insights into the role of hepatocyte PPARα activity in response to fasting

…, S Smati, A Marrot, F Lasserre, C Naylies… - Molecular and cellular …, 2018 - Elsevier
… Amplification conditions were as follows: 95 C for 15 min; followed by 35 cycles of 94 C for
1 min, 65 C for 1 min, and 72 C for 1 min; and a final cycle of 72 C for 10 min. This reaction …

[HTML][HTML] Haem iron reshapes colonic luminal environment: impact on mucosal homeostasis and microbiome through aldehyde formation

…, V Tondereau, Y Lippi, C Naylies, L Peyriga, C Canlet… - Microbiome, 2019 - Springer
… : a first one-hold stage at 95 C for 10 min followed by 40 cycles (95 C for 15 s and 60 C for
30 s) and a final extending step (95 C for 15 s, 60 C for 1 min, and 95 C for 15 s) for melt curve …

Implication of VelB in the development, pathogenicity, and secondary metabolism of Penicillium expansum

…, C Zetina-Serrano, O Rocher, C Naylies… - Postharvest Biology and …, 2023 - Elsevier
Penicillium expansum is the main cause of blue mold disease and the main producer of
patulin in apple-derived products. This fungus also produces a wide variety of secondary …

Impact of veA on the development, aggressiveness, dissemination and secondary metabolism of Penicillium expansum

…, SP Snini, S Tadrist, S Bailly, C Naylies… - Molecular Plant …, 2018 - Wiley Online Library
… (A) and the null mutant PeΔveA strain (B) stored at 25 C in the light for 1 month. (C) An
apple inoculated with the WT strain and stored at 25 C in the dark for 1 month. (D) A piece of …

The protective role of liver X receptor (LXR) during fumonisin B1-induced hepatotoxicity

…, Y Lippi, C Naylies, J Laffitte, C Bétoulières… - Archives of …, 2019 - Springer
Fumonisin B1 (FB1), a congener of fumonisins produced by Fusarium species, is the most
abundant and most toxicologically active fumonisin. FB1 causes severe mycotoxicosis in …

[PDF][PDF] The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression

…, E Nédélec, V Gigot, L Smith, C Naylies, C Sommer… - Cell Reports, 2022 - cell.com
… The amplification conditions were as follows: 95 C for 5 min, followed by 35 cycles of 94
C for 30 s, 65 C for 30 s, and 72 C for 45 s, and a final cycle of 72 C for 7 min. This reaction …

Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target

…, J Wan, C Sommer, C Naylies, A Batut, C Lukowicz… - Gut, 2022 - gut.bmj.com
Objective We evaluated the influence of sex on the pathophysiology of non-alcoholic fatty
liver disease (NAFLD). We investigated diet-induced phenotypic responses to define sex-…