The conserved formin homology 2 (FH2) domain nucleates actin filaments and remains bound
to the barbed end of the growing filament. Here we report the crystal structure of the yeast …

… ATG9 proteins vary in their chain lengths, ranging from ~700 to 1,000 residues, with both
the N and C termini being substantially different among species. Common to all species is the …

… In our structure, the C-terminal tail of ATG12 folds back onto its own UFD through … of the
C-terminal tail of ATG12 has not been observed among structures of ubiquitin-like proteins; the C …

… , involving its own C-terproximately parallel to its long axis (… face is formed by stacking of
helices A and C. The two DIDs … Highest surface conservation is observed near the C termini of …

… ATG2 contains two additional conserved regions: an ‘ATG_C’ domain, also registered in
Pfam and located at the end of the C-terminus; and another short region preceding the ATG_C …

… To identify the C-terminal region, we fused an MBP to the C terminus and also inserted
an … In contrast to our previous labeling experiments, the MBP molecules in these C-terminal …

… in cells coexpressing an L1062D mutant C terminus (Fig. S1). … C termini are mutually
autoinhibitory, with the N terminus blocking the actin assembly activity of the FH2 domain and the C …

… Then we incubated DC-LC3in-D5 with purified LC3B protein (Figure 4 C) or a peptide
truncated from LC3B with Lys49 and Lys51 (marked as red) included (Figure 4 D; Figure S3). DC-…

… or Cdc42; constructs with PhyB at the C terminus did not express in bacteria or expressed
… 2 C and D). We then measured WASP activity toward Arp2/3 complex in the PhyB or Pif3 N …

… This positioning allows the catalytic cysteine of Atg3 E2core to face that of Atg7 in its C-terminal
domain, facilitating the transfer of Atg3 to Atg7. We previously showed that the …