User profiles for C. Rieker

Claude Rieker

Zimmer Biomet
Verified email at a3.epfl.ch
Cited by 1898

Development and validation of a second-generation metal-on-metal bearing: laboratory studies and analysis of retrievals

CB Rieker, R Schön, P Köttig - The Journal of arthroplasty, 2004 - Elsevier
This paper summarizes hip simulator and retrieval studies that were done to optimize 1 design
of a second-generation metal-on-metal hip replacement. It was determined that clearance …

Influence of the clearance on in-vitro tribology of large diameter metal-on-metal articulations pertaining to resurfacing hip implants

CB Rieker, R Schön, R Konrad… - Orthopedic …, 2005 - orthopedic.theclinics.com
Rieker CB … During the test, the lubricant temperature was maintained at 37C ± 2C, and
the lubricant was replaced after every 0.5 million cycles. … Temperature 37C

[PDF][PDF] Alternative materials to improve total hip replacement tribology

…, R Lappalainen, O Muratoglu, C Rieker… - Acta orthopaedica …, 2003 - researchgate.net
An improvement in tribology of bearing surfaces is an effective means of increasing the
longevity of total hip replacement (THR). Currently, 3 approaches are available to achieve this …

Analysis of 118 second-generation metal-on-metal retrieved hip implants

HP Sieber, CB Rieker, P Köttig - The Journal of Bone & Joint …, 1999 - boneandjoint.org.uk
Osteolysis is due to particulate wear debris and is responsible for the long-term failure of
total hip replacements. It has stimulated the development of alternative joint surfaces such as …

Transneuronal propagation of mutant huntingtin contributes to non–cell autonomous pathology in neurons

E Pecho-Vrieseling, C Rieker, S Fuchs… - Nature …, 2014 - nature.com
… Slices were fixed for 5 min in 4% paraformaldehyde (vol/vol) at 35 C, washed in PBS and
blocked for 1 h at 21–23 C in PBS containing 0.1% Triton X-100 and 1% BSA (blocking solution…

Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling

C Rieker, D Engblom, G Kreiner… - Journal of …, 2011 - Soc Neuroscience
C, Quantification of visible nucleoli in four PD samples at different pathology progression
show a dramatic decrease of visible nucleoli in TH + neurons compared with controls. Scale bar…

Metal-on-metal articulation for artificial hip joints: laboratory study and clinical results

…, R Schön, H Weber, C Rieker - Proceedings of the …, 1996 - journals.sagepub.com
As wear is inevitable with artificial joint replacement, it has to be minimized to avoid possible
aseptic loosening following osteolysis due to particle-initiated foreign body reaction. Co-Cr-…

Activation of an endogenous suicide response after perturbation of rRNA synthesis leads to neurodegeneration in mice

R Parlato, G Kreiner, G Erdmann, C Rieker… - Journal of …, 2008 - Soc Neuroscience
… The primary antibodies were incubated overnight at 4C. Biotin-conjugated secondary antibody
C–F, Nonradioactive in situ hybridization on coronal paraffin sections from control (C, E) …

[HTML][HTML] Neuropathology in mice expressing mouse alpha-synuclein

C Rieker, KK Dev, K Lehnhoff, S Barbieri, I Ksiazek… - PloS one, 2011 - journals.plos.org
… heating at 90C for 60 min before incubation with anti-α-synuclein; microwave heating at
90C for 30 min before anti-GFAP and anti-phosphotyrosine anti-ubiquitin treatment at 37C, 30 …

Apolipoprotein E4 expression causes gain of toxic function in isogenic human induced pluripotent stem cell-derived endothelial cells

C Rieker, E Migliavacca, A Vaucher… - … , and vascular biology, 2019 - Am Heart Assoc
Objective: The ApoE (apolipoprotein) allele epsilon 4 is a major genetic risk factor for
Alzheimer disease, cardiovascular disorders, and stroke, indicating that it significantly impacts …