Inflammatory processes are important participants in the pathophysiology of hypertension
and cardiovascular disease. The identification of the mechanisms leading to the activation of …

More than 80% of patients with type 2 diabetes mellitus develop hypertension, and approx.
20% of patients with hypertension develop diabetes. This combination of cardiovascular risk …

Endothelium plays a fundamental role in the cardiovascular system, forming an interface
between blood and adjacent tissues by regulating the vascular tone through the synthesis of …

Background— Enhanced production of reactive oxygen species (ROS) has been recognized
as the major determinant of age-related endothelial dysfunction. The p66 shc protein …

Hypertension is associated with vascular changes characterised by remodelling, endothelial
dysfunction and hyperreactivity. Cellular processes underlying these perturbations include …

… for MFN2 was only around 65% (Figure S1C), possibly explaining why we could not detect
… In conclusion, ERK-phosphorylated MFN1 favors cytochrome c release by increasing BAK …

… C for 5 seconds, 35 cycles of 95C for 30 seconds, 54C for 30 seconds, 72C for 30 seconds,
and extension for 5 minutes at 72C. … 94C for 5 minutes, 30 cycles of 94C for 30 seconds, 57C …

Essential hypertension is characterized by increased peripheral vascular resistance to
blood flow. The endothelium is a crucial regulator of vascular tone. Its function is impaired in …

Some antihypertensive agents may improve resistance artery remodeling in hypertensive
patients whereas other agents may not, for similar blood pressure reduction. We questioned …

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) associates with a considerable high rate of mortality and represents …