… b, c, Cumulative distribution function plot (individual samples were ranked independently for
… SNVs and MNVs (b) and indels and SVs (c). The median for each tumour type is indicated …

… can detect water within most shale samples, even after they have been oven dried for 24
h at 100 C; less aggressively dried shale samples (eg 60 C and vacuum) have appreciable …

… c Comparison of expected vs actual copy number changes for the Hartwig cohort. SV … c
Phasing of structural variants can be determined when breakend assembly contigs span multiple …

… The HLA-I: somatic alterations in the HLA-A, HLA-B and HLA-C genes have been extensively
… We defined LOH for HLA-A, HLA-B and HLA-C as those cases with a minor allele ploidy <…

… Shale), San Diego County Health and Human Services Agency (Mr. Mastin), San Diego;
and the Department of Surgery, Naval Medical Center San Diego, San Diego (Dr. C. Shale), …

… Note that foldback inversions have a distinct length distribution and are shown separately
in Figure S4C. (C) Counts of deletions and duplications in complex clusters per sample both …

We have developed a novel, integrated and comprehensive purity, ploidy, structural variant
and copy number somatic analysis toolkit for whole genome sequencing data of paired tumor…

Background In ∼3%-5% of patients with metastatic disease, tumor origin remains unknown
despite modern imaging techniques and extensive pathology work-up. With long diagnostic …

… Bell C. The Bridgewater Treatise. The Hand: Its Mechanism and Vital Endowments as
Evincing Design. … Shale, MD … Shale, MD …

In this essay we use clinical evidence and knowledge of anatomy to examine the relationship
between blood flow and formation of congenital extrahepatic portosystemic shunts in dogs …