… (C) Presentation of yearly number of publications of the top-five most prolific countries. (D)
Geographical distribution of hPSC research. For each country, the total number of articles in …

Two leading European professional societies, the European Society of Human Genetics
and the European Society for Human Reproduction and Embryology, have worked together …

BACKGROUND There is an increasing body of evidence that human pluripotent stem cells (hPSCs)
are prone to (epi)genetic instability during in vitro culture. This review aims at giving …

… The enzyme mix of the GenomiPhi Kit must be stored at −70 C (or −80 C) and all other
components may be stored at −20 C. Thaw components on ice and maintain at 0–4 C during …

… Spits designed the study, performed part of the aCGH analysis and G-bandings and wrote
the … KS is the supervisor of C. Spits, IM and AM and contributed to the design of the study. The …

The scarcity of genomic DNA can be a limiting factor in some fields of genetic research. One
of the methods developed to overcome this difficulty is whole genome amplification (WGA). …

… The samples were stored at −80C for at least 30 min and … for local background and only spots
with signal intensities at least 1.2-… A mean of all remaining spots of each chromosome was …

STUDY QUESTION What are the aneuploidy rates and incidence of mosaicism in good-quality
human preimplantation embryos. SUMMARY ANSWER High-level mosaicism and …

… C, 30 cycles of 30 s at 94C, 30 s at 58C and 30 s at 72C. Agarose gel electrophoresis was
performed with 1 µl of the molecular weight marker VIII (Roche Diagnostics GmbH, Mannheim…

… A final extension step of 7 min at 72 C was applied. Primer sequences are … C, 15 cycles of
10 s at 98 C, 30 s at 65 C, and 30 s at 72 C, followed by the final extension step of 5 min at 72 C…