User profiles for C. Spits
Claudia SpitsVrije Universiteit Brussel Verified email at vub.ac.be Cited by 3967 |
The consequences of recurrent genetic and epigenetic variants in human pluripotent stem cells
… (C) Presentation of yearly number of publications of the top-five most prolific countries. (D)
Geographical distribution of hPSC research. For each country, the total number of articles in …
Geographical distribution of hPSC research. For each country, the total number of articles in …
Recent developments in genetics and medically-assisted reproduction: from research to clinical applications
Two leading European professional societies, the European Society of Human Genetics
and the European Society for Human Reproduction and Embryology, have worked together …
and the European Society for Human Reproduction and Embryology, have worked together …
Genetic and epigenetic instability in human pluripotent stem cells
BACKGROUND There is an increasing body of evidence that human pluripotent stem cells (hPSCs)
are prone to (epi)genetic instability during in vitro culture. This review aims at giving …
are prone to (epi)genetic instability during in vitro culture. This review aims at giving …
Whole-genome multiple displacement amplification from single cells
C Spits, C Le Caignec, M De Rycke, L Van Haute… - Nature protocols, 2006 - nature.com
… The enzyme mix of the GenomiPhi Kit must be stored at −70 C (or −80 C) and all other
components may be stored at −20 C. Thaw components on ice and maintain at 0–4 C during …
components may be stored at −20 C. Thaw components on ice and maintain at 0–4 C during …
Recurrent chromosomal abnormalities in human embryonic stem cells
C Spits, I Mateizel, M Geens, A Mertzanidou… - Nature …, 2008 - nature.com
… Spits designed the study, performed part of the aCGH analysis and G-bandings and wrote
the … KS is the supervisor of C. Spits, IM and AM and contributed to the design of the study. The …
the … KS is the supervisor of C. Spits, IM and AM and contributed to the design of the study. The …
Optimization and evaluation of single‐cell whole‐genome multiple displacement amplification
C Spits, C Le Caignec, M De Rycke… - Human …, 2006 - Wiley Online Library
The scarcity of genomic DNA can be a limiting factor in some fields of genetic research. One
of the methods developed to overcome this difficulty is whole genome amplification (WGA). …
of the methods developed to overcome this difficulty is whole genome amplification (WGA). …
Single-cell chromosomal imbalances detection by array CGH
… The samples were stored at −80C for at least 30 min and … for local background and only spots
with signal intensities at least 1.2-… A mean of all remaining spots of each chromosome was …
with signal intensities at least 1.2-… A mean of all remaining spots of each chromosome was …
Microarray analysis reveals abnormal chromosomal complements in over 70% of 14 normally developing human embryos
A Mertzanidou, L Wilton, J Cheng, C Spits… - Human …, 2013 - academic.oup.com
STUDY QUESTION What are the aneuploidy rates and incidence of mosaicism in good-quality
human preimplantation embryos. SUMMARY ANSWER High-level mosaicism and …
human preimplantation embryos. SUMMARY ANSWER High-level mosaicism and …
Gain of 20q11. 21 in human embryonic stem cells improves cell survival by increased expression of Bcl-xL
…, C Heirman, K Breckpot, C Spits - Molecular human …, 2014 - academic.oup.com
… C, 30 cycles of 30 s at 94C, 30 s at 58C and 30 s at 72C. Agarose gel electrophoresis was
performed with 1 µl of the molecular weight marker VIII (Roche Diagnostics GmbH, Mannheim…
performed with 1 µl of the molecular weight marker VIII (Roche Diagnostics GmbH, Mannheim…
[PDF][PDF] CpG methylation, a parent-of-origin effect for maternal-biased transmission of congenital myotonic dystrophy
… A final extension step of 7 min at 72 C was applied. Primer sequences are … C, 15 cycles of
10 s at 98 C, 30 s at 65 C, and 30 s at 72 C, followed by the final extension step of 5 min at 72 C…
10 s at 98 C, 30 s at 65 C, and 30 s at 72 C, followed by the final extension step of 5 min at 72 C…