All animals must detect noxious stimuli to initiate protective behavior, but the evolutionary
origin of nociceptive systems is not well understood. Here we show that noxious heat and …

Mechanisms that enable injury responses to prompt regenerative outgrowth are not well
understood. Planarians can regenerate essentially any tissue removed by wounding, even after …

Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease
characterized by degeneration of lower motor neurons (LMNs), causing muscle weakness, …

… Duplex siRNA was prepared by annealing the single-stranded RNAs in annealing buffer
for 1 h at 37C after a 2-min incubation at 95C. For target mRNA cleavage reactions, unlabeled …

Cell growth and proliferation are pivotal for final organ and body size definition. p53-related
protein kinase (Bud32/PRPK) has been identified as a protein involved in proliferation …

Regeneration involves precise control of cell fate to produce an appropriate complement of
tissues formed within a blastema. Several chromatin‐modifying complexes have been …

The unique geography of Chile encompasses a wide diversity of ecosystems and a rich
biodiversity. However, the platyhelminth fauna has been poorly studied. The aim of this work is …

Invasive species form an important threat to autochthonous biodiversity and ecosystems, as
they may negatively affect native species. Pentacoelum kazukolinda is an invasive …

All animals must detect noxious stimuli to initiate protective behavior, but the evolutionary
origin of nociceptive systems is not well understood. Here, we show that a remarkably …

There is considerable medical interest in discovering mechanisms that enable adult stem
cells to repair injured tissue. A substantial effort has been spent engineering novel …