User profiles for C. Wilhelm-Benartzi

Charlotte S. Wilhelm-Benartzi

Cardiff University
Verified email at cardiff.ac.uk
Cited by 3967

Whole–genome characterization of chemoresistant ovarian cancer

…, MCJ Quinn, S Kazakoff, K Quek, C Wilhelm-Benartzi… - Nature, 2015 - nature.com
… Asterisk indicates statistical significance of C(C>T)C using a test of equal or given
proportions across the cohort after a Fisher’s exact test (two-sided) on individual cases (P <0.05). …

Plasma antibodies to oral bacteria and risk of pancreatic cancer in a large European prospective cohort study

DS Michaud, J Izard, CS Wilhelm-Benartzi, DH You… - Gut, 2013 - gut.bmj.com
Objective Examine the relationship between antibodies to 25 oral bacteria and pancreatic
cancer risk in a prospective cohort study. Design We measured antibodies to oral bacteria in …

Candidate DNA methylation drivers of acquired cisplatin resistance in ovarian cancer identified by methylome and expression profiling

…, A Siddiq, AJ Walley, CSM Wilhelm-Benartzi… - Oncogene, 2012 - nature.com
… ) and amplification parameters: 95 C for 3 min, 42 cycles of 95 C for 10 s, 60 C for 10 s and
72 C for 30 s, followed by 95 C for 10 s and temperature increments from 72–95 C for 5 s. …

Poised epigenetic states and acquired drug resistance in cancer

…, E Curry, L Magnani, CS Wilhelm-Benartzi… - Nature Reviews …, 2014 - nature.com
Epigenetic events, which are somatically inherited through cell division, are potential drivers
of acquired drug resistance in cancer. The high rate of epigenetic change in tumours …

[HTML][HTML] Review of processing and analysis methods for DNA methylation array data

CS Wilhelm-Benartzi, DC Koestler, MR Karagas… - British journal of …, 2013 - nature.com
The promise of epigenome-wide association studies and cancer-specific somatic DNA
methylation changes in improving our understanding of cancer, coupled with the decreasing cost …

In Utero Exposures, Infant Growth, and DNA Methylation of Repetitive Elements and Developmentally Related Genes in Human Placenta

CS Wilhelm-Benartzi, EA Houseman… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: Fetal programming describes the theory linking environmental conditions during
embryonic and fetal development with risk of diseases later in life. Environmental insults in …

Birthweight is associated with DNA promoter methylation of the glucocorticoid receptor in human placenta

…, MA Maccani, DC Koestler, C Wilhelm-Benartzi… - Epigenetics, 2011 - Taylor & Francis
Birthweight has been associated with a number of health outcomes throughout life. Crucial
to proper infant growth and development is the placenta, and alterations to placental gene …

A model to predict vaginal delivery in nulliparous women based on maternal characteristics and intrapartum ultrasound

TM Eggebø, C Wilhelm-Benartzi, WA Hassan… - American journal of …, 2015 - Elsevier
Objective Accurate prediction of whether a nulliparous woman will have a vaginal delivery
would be a major advance in obstetrics. The objective of the study was to develop such a …

Platinum-based chemotherapy induces methylation changes in blood DNA associated with overall survival in patients with ovarian cancer

…, J Gallon, E Loomis, K Flower, C Wilhelm-Benartzi… - Clinical Cancer …, 2017 - AACR
Purpose: DNA damage repair can lead to epigenetic changes. DNA mismatch repair
proteins bind to platinum DNA adducts and at sites of DNA damage can recruit the DNA …

Radiological predictors of cytoreductive outcomes in patients with advanced ovarian cancer

J Borley, C WilhelmBenartzi, J Yazbek… - … Journal of Obstetrics …, 2015 - Wiley Online Library
Objective To assess site of disease on preoperative computed tomography ( CT ) to predict
surgical debulking in patients with ovarian cancer. Design Two‐phase retrospective cohort …