Broadly neutralizing antibodies target the coronavirus fusion peptide

…, Y Cong, L Wang, L Purser, JK Williams, CW Pyo… - Science, 2022 - science.org
The potential for future coronavirus outbreaks highlights the need to broadly target this group
of pathogens. We used an epitope-agnostic approach to identify six monoclonal antibodies …

[HTML][HTML] Different Patterns of Evolution in the Centromeric and Telomeric Regions of Group A and B Haplotypes of the Human Killer Cell Ig-Like Receptor Locus

CW Pyo, LA Guethlein, Q Vu, R Wang, L Abi-Rached… - PloS one, 2010 - journals.plos.org
The fast evolving human KIR gene family encodes variable lymphocyte receptors specific for
polymorphic HLA class I determinants. Nucleotide sequences for 24 representative human …

[PDF][PDF] Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses

…, L Wang, L Purser, AJR Cooper, JK Williams, CW Pyo… - Cell host & …, 2023 - cell.com
Humanity has faced three recent outbreaks of novel betacoronaviruses, emphasizing the
need to develop approaches that broadly target coronaviruses. Here, we identify 55 …

Beamforming codebook design and performance evaluation for 60GHz wideband WPANs

J Wang, Z Lan, CS Sum, CW Pyo, J Gao… - 2009 IEEE 70th …, 2009 - ieeexplore.ieee.org
The paper proposes a codebook design to support beamforming mechanism in a wide band
millimeter-wave 60 GHz wireless personal area networks (60 GHz WPANs) in a realistic …

[HTML][HTML] Antibody Fc effector functions and IgG3 associate with decreased HIV-1 risk

…, M Shao, NL Yates, F Feely, CW Pyo… - The Journal of …, 2019 - Am Soc Clin Investig
HVTN 505 is a preventative vaccine efficacy trial testing DNA followed by recombinant
adenovirus serotype 5 (rAd5) in circumcised, Ad5-seronegative men and transgendered persons …

[HTML][HTML] FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial

…, G Kijak, G Ferrari, R Thomas, CW Pyo… - The Journal of …, 2014 - Am Soc Clin Investig
The phase III RV144 HIV-1 vaccine trial estimated vaccine efficacy (VE) to be 31.2%. This
trial demonstrated that the presence of HIV-1–specific IgG-binding Abs to envelope (Env) …

[HTML][HTML] The genome sequence of the Antarctic bullhead notothen reveals evolutionary adaptations to a cold environment

SC Shin, DH Ahn, SJ Kim, CW Pyo, H Lee, MK Kim… - Genome biology, 2014 - Springer
Background Antarctic fish have adapted to the freezing waters of the Southern Ocean.
Representative adaptations to this harsh environment include a constitutive heat shock response …

Next-Generation Sequencing Reveals That HLA-DRB3, -DRB4, and -DRB5 May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes

…, M Persson, U Samuelsson, E Örtqvist, CW Pyo… - Diabetes, 2016 - Am Diabetes Assoc
The possible contribution of HLA-DRB3, -DRB4, and -DRB5 alleles to type 1 diabetes risk
and to insulin autoantibody (IAA), GAD65 (GAD autoantibody [GADA]), IA-2 antigen (IA-2A), or …

Cognitive communication in TV white spaces: An overview of regulations, standards, and technology [Accepted From Open Call]

…, J Wang, C Song, CW Pyo… - IEEE …, 2013 - ieeexplore.ieee.org
This article presents the latest developments in regulatory status and standardization
initiatives in the field of TV white space cognitive communication systems. Updates on recent …

[HTML][HTML] Recombinant structures expand and contract inter and intragenic diversification at the KIR locus

CW Pyo, R Wang, Q Vu, N Cereb, SY Yang, FM Duh… - BMC genomics, 2013 - Springer
Background The human KIR genes are arranged in at least six major gene-content haplotypes,
all of which are combinations of four centromeric and two telomeric motifs. Several less …