Ferroptosis is a form of regulated necrotic cell death controlled by glutathione peroxidase 4 (GPX4).
At present, mechanisms that could predict sensitivity and/or resistance and that may …

Ferroptosis is an iron-dependent form of necrotic cell death marked by oxidative damage to
phospholipids 1 , 2 . To date, ferroptosis has been thought to be controlled only by the …

The present review summarizes up-to-date evidence addressing the frequently discussed
clinical controversies regarding the use of immune checkpoint inhibitors (ICIs) in cancer …

Master regulators of the epithelial-mesenchymal transition such as Twist1 and Snail1 have
been implicated in invasiveness and the generation of cancer stem cells, but their persistent …

We present an organoid regeneration assay in which freshly isolated human mammary
epithelial cells are cultured in adherent or floating collagen gels, corresponding to a rigid or …

… Percentages of covered area in each colour channel (PHBEC colony formation) and
percentages of positive cells (MCF10A colony formation) were quantified using ImageJ (FIJI, 64 bit) …

Epithelial branch elongation is a central developmental process during branching morphogenesis
in diverse organs. This fundamental growth process into large arborized epithelial …

… CH has received grants or contracts from Barts Charity, Medical Research Council, United
Kingdom, and British Skin Foundation, consulting fees from AMLo Biosciences, Leo Pharma, …

… We thank all members of the Scheel group at the Helmholtz Center Munich for sharing
experimental expertise. This work was supported by the Transluminal-B and IntegrateTN …

Purpose To evaluate the pan-immune-inflammation value (PIV) and systemic immune-inflammation
index (SII) in patients with cutaneous melanoma (CM) under immune checkpoint …