To identify risk factors for hip fracture in men, the authors conducted a case-control study
involving 20 hospitals in Philadelphia, Pennsylvania, and 14 hospitals in Kaiser Permanente …

Organ fibrosis is a shared endpoint of many diseases, yet underlying mechanisms are not
well understood. Several pathways governed by the primary cilium, a sensory antenna …

Joubert syndrome (JBTS) is a genetically heterogeneous autosomal-recessive
neurodevelopmental ciliopathy. We investigated further the underlying genetic etiology of Joubert …

Nephronophthisis (NPHP) is the major cause of pediatric renal failure, yet the disease remains
poorly understood, partly due to the lack of appropriate animal models. Joubert syndrome …

Pigeons were trained in an operant, go/no-go, discrimination by successive presentations of
discrete, positive and negative trials. In separate groups, the rate of discriminaion learning …

Joubert syndrome (JBTS) is the archetypal ciliopathy caused by mutation of genes
encoding ciliary proteins leading to multi-system phenotypes, including a cerebello-retinal-renal …

Each pair of subjects in this experiment was required to discuss a topic on which they initially
disagreed. The persuasiveness of one over the other was defined as shorter latency of first …

Genetic treatments of renal ciliopathies leading to cystic kidney disease would provide a
real advance in current therapies. Mutations in CEP290 underlie a ciliopathy called Joubert …

Denys–Drash syndrome (DDS) is caused by dominant mutations of the Wilms' tumour suppressor
gene, WT1 , and characterized by a nephropathy involving diffuse mesangial sclerosis…

The Nef gene product is a regulatory protein of HIV whose biological function is poorly
understood. Nef has been thought to have a negative effect on viral replication in vitro but has …