On the basis of ultrastructural parameters, the concept was formulated that asymmetric Type
I and symmetric Type II synapses are excitatory and inhibitory, respectively. This “functional …

Parkinson’s disease is caused by a complex interplay of genetic and environmental factors.
Although a number of independent molecular pathways and processes have been …

Levels of sociability are continuously distributed in the general population, and decreased
sociability represents an early manifestation of several brain disorders. Here, we investigated …

Parkinson’s disease (PD) is characterized by the degeneration of dopaminergic neurons in
the substantia nigra and the formation of Lewy bodies. The mechanisms underlying these …

Amyotrophic lateral sclerosis (ALS) is a severe, progressive and ultimately fatal motor neuron
disease caused by a combination of genetic and environmental factors, but its underlying …

Parkinson’s disease (PD) is characterized by dopaminergic (DA) neuron death in the
substantia nigra (SN) and subsequent striatal adaptations. Mice treated with the neurotoxin 1-…

Parkinson’s disease (PD) is characterized by the degeneration of dopaminergic (DA)
neurons in the substantia nigra pars compacta (SNpc), resulting in motor and non-motor …

Difficulties with sociability include a tendency to avoid social contacts and activities, and to
prefer being alone rather than being with others. While sociability is a continuously distributed …

… Rouwette T, Klemann K, Gaszner B, Scheffer GJ, Roubos EW, Scheenen WJ, Vissers K,
Kozicz T. Differential responses of corticotropin-releasing factor and urocortin 1 to acute pain …

… Cornelius Jacobus Hendricus Maria Klemann geboren op 28 januari 1986 te Tilburg …
Cover: Photographed by Hans Eikmans in the former seminary Haarendael (Haaren, The …