User profiles for CN Robson
 | Craig RobsonProfessor of molecular urology Verified email at ncl.ac.uk Cited by 15066 |
Cellular functions of TIP60
V Sapountzi, IR Logan, CN Robson - … journal of biochemistry & cell biology, 2006 - Elsevier
TIP60 was originally identified as a cellular acetyltransferase protein that interacts with HIV-1
Tat. As a consequence, the role of TIP60 in transcriptional regulation has been investigated …
Tat. As a consequence, the role of TIP60 in transcriptional regulation has been investigated …
[HTML][HTML] Optimal management of metastatic castration-resistant prostate cancer: highlights from a European Expert Consensus Panel
…, S Oudard, TM De Reijke, CN Robson… - European Journal of …, 2014 - Elsevier
… Robson has no relevant relationships to report. Maria De Santis has received consulting
fees from Amgen, Astellas, Bayer, Dendreon, Genex, GlaxoSmithKline, Ipse, Janssen, Novartis, …
fees from Amgen, Astellas, Bayer, Dendreon, Genex, GlaxoSmithKline, Ipse, Janssen, Novartis, …
Regulation of the androgen receptor by post-translational modifications.
The androgen receptor (AR) is a key molecule in prostate cancer and Kennedy's disease.
Understanding the regulatory mechanisms of this steroid receptor is important in the …
Understanding the regulatory mechanisms of this steroid receptor is important in the …
CD133, a novel marker for human prostatic epithelial stem cells
GD Richardson, CN Robson, SH Lang… - Journal of cell …, 2004 - journals.biologists.com
Stem cells are clonogenic cells with self-renewal and differentiation properties, which may
represent a major target for genetic damage leading to prostate cancer and benign prostatic …
represent a major target for genetic damage leading to prostate cancer and benign prostatic …
Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer
…, S Cook, HY Leung, DE Neal, CN Robson - The …, 2004 - Wiley Online Library
… Robson, School of Surgical and Reproductive Sciences, The Medical School, University of
Newcastle upon Tyne, NE2 4HH, Newcastle upon Tyne, UK. E-mail: cnrobson… Mary Robinson…
Newcastle upon Tyne, NE2 4HH, Newcastle upon Tyne, UK. E-mail: cnrobson… Mary Robinson…
[HTML][HTML] Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor
…, IR Logan, S Cook, DE Neal, CN Robson - Journal of Biological …, 2002 - ASBMB
The androgen receptor (AR), a member of the nuclear hormone receptor superfamily, is
thought to play an important role in the development of prostate cancer. The AR is a hormone-…
thought to play an important role in the development of prostate cancer. The AR is a hormone-…
Isolation of cDNA clones encoding a human apurini/apyrimidinic endonuclease that corects DNA repair and mutagenisis defects in E.coli xth …
CN Robson, ID Hickson - Nucleic acids research, 1991 - academic.oup.com
Apurinic/apyrimidinic (AP) sites in cellular DNA are considered to be both cytotoxic and
mutagenic, and can arise spontaneously or following exposure to DNA damaging agents. We …
mutagenic, and can arise spontaneously or following exposure to DNA damaging agents. We …
Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding
LJ Walker, CN Robson, E Black… - … and cellular biology, 1993 - Taylor & Francis
The DNA binding activity of the c-jun proto-oncogene product is inhibited by oxidation of a
specific cysteine residue (Cys-252) in the DNA binding domain. Jun protein inactivated by …
specific cysteine residue (Cys-252) in the DNA binding domain. Jun protein inactivated by …
[HTML][HTML] Tip60 is a nuclear hormone receptor coactivator
The androgen receptor (AR) is a member of the nuclear hormone receptor superfamily.
Recent work in this field has been focused upon defining the mechanisms of transcriptional …
Recent work in this field has been focused upon defining the mechanisms of transcriptional …
Expression of Tip60, an androgen receptor coactivator, and its role in prostate cancer development
…, ME Brady, S Cook, HY Leung, DE Neal, CN Robson - Oncogene, 2003 - nature.com
Prostate cancer (CaP) is initially androgen sensitive and responsive to hormone ablation
therapy. However, cancer growth recurs despite androgen deprivation in the majority of cases …
therapy. However, cancer growth recurs despite androgen deprivation in the majority of cases …