[HTML][HTML] Radiological diagnosis in lung disease: factoring treatment options into the choice of diagnostic modality

MO Wielpütz, CP Heußel, FJF Herth… - Deutsches Ärzteblatt …, 2014 - ncbi.nlm.nih.gov
Background Chest X-ray, computed tomography (CT), and magnetic resonance imaging (MRI)
each have characteristic advantages and disadvantages that need to be considered in …

Fibroblast activation protein–specific PET/CT imaging in fibrotic interstitial lung diseases and lung cancer: a translational exploratory study

…, PE Huber, A von Deimling, CP Heußel… - Journal of nuclear …, 2022 - Soc Nuclear Med
Interstitial lung diseases (ILDs) comprise over 200 parenchymal lung disorders. Among
them, fibrosing ILDs, especially idiopathic pulmonary fibrosis, are associated with a poor …

Potential of ChatGPT and GPT-4 for data mining of free-text CT reports on lung cancer

…, CA Fink, M Moll, J Kroschke, L Dulz, CP Heußel… - Radiology, 2023 - pubs.rsna.org
Background The latest large language models (LLMs) solve unseen problems via user-defined
text prompts without the need for retraining, offering potentially more efficient information …

Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: analysis of the first 3,000 Heidelberg cases

…, M Faehling, JR Fischer, CP Heußel… - … Journal of Cancer, 2019 - Wiley Online Library
Tyrosine kinase inhibitors currently confer the greatest survival gain for nonsmall cell lung
cancer (NSCLC) patients with actionable genetic alterations. Simultaneously, the increasing …

Glymphatic pathway of gadolinium-based contrast agents through the brain: overlooked and misinterpreted

…, S Bickelhaupt, M Forsting, CP Heußel… - Investigative …, 2019 - journals.lww.com
Background The “glymphatic system”(GS), a brain-wide network of cerebrospinal fluid
microcirculation, supplies a pathway through and out of the central nervous system (CNS); …

Identification of a highly lethal V3+TP53+ subset in ALK+ lung adenocarcinoma

…, R Penzel, FJ Herth, CP Heußel… - … Journal of Cancer, 2019 - Wiley Online Library
Tyrosine kinase inhibitors (TKI) have improved prognosis in metastatic anaplastic lymphoma
kinase (ALK)‐driven lung adenocarcinoma, but patient outcomes vary widely. We …

Transbronchial cryobiopsy increases diagnostic confidence in interstitial lung disease: a prospective multicentre trial

…, M Horger, F Fend, A Warth, CP Heußel… - European …, 2020 - Eur Respiratory Soc
… Conflict of interest: CP Heußel reports personal fees from Novartis, Basilea and Bayer,
outside the submitted work. In addition, Dr Heußel has a patent Method and Device For …

A gene expression signature associated with B cells predicts benefit from immune checkpoint blockade in lung adenocarcinoma

…, J Glade, M Allgäuer, M Kriegsmann, CP Heußel… - …, 2021 - Taylor & Francis
Immune checkpoint blockade (ICB) expands the therapeutic options for metastatic lung
cancer nowadays representing a standard frontline strategy as monotherapy or combination …

[HTML][HTML] Deciphering the immunosuppressive tumor microenvironment in ALK-and EGFR-positive lung adenocarcinoma

…, M Allgäuer, M Kriegsmann, CP Heußel… - Cancer Immunology …, 2022 - Springer
Introduction The advent of immune checkpoint blockade (ICB) has led to significantly
improved disease outcome in lung adenocarcinoma (ADC), but response of ALK/EGFR-positive …

High‐resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD

…, MA Schneider, K Quast, J Hey, CP Heußel… - The EMBO …, 2023 - embopress.org
Patients with chronic obstructive pulmonary disease (COPD) are still waiting for curative
treatments. Considering its environmental cause, we hypothesized that COPD will be …