… One of us (CV Gabel) has used these clamps to perform laser axotomy and long-term
imaging of axonal regrowth in multiple animals simultaneously. Several groups have developed …

The toxicity of misfolded proteins and mitochondrial dysfunction are pivotal factors that
promote age-associated functional neuronal decline and neurodegenerative disease 1 , 2 . …

One advantage of the nematode Caenorhabditis elegans as a model organism is its
suitability for in vivo optical microscopy. Imaging C. elegans often requires animals to be …

A protonmotive force (pmf) across the cell's inner membrane powers the flagellar rotary motor
of Escherichia coli. Speed is known to be proportional to pmf when viscous loads are heavy…

Many animals use their olfactory systems to learn to avoid dangers, but how neural circuits
encode naive and learned olfactory preferences, and switch between those preferences, is …

Mitochondrial transport is crucial for neuronal and axonal physiology. However, whether and
how it impacts neuronal injury responses, such as neuronal survival and axon regeneration…

Background Caenorhabditis elegans actively crawls down thermal gradients until it reaches
the temperature of its prior cultivation, exhibiting what is called cryophilic movement. Implicit …

The nematode Caenorhabditis elegans deliberately crawls toward the negative pole in an
electric field. By quantifying the movements of individual worms navigating electric fields, we …

Our understanding of the operation of neurons and neuronal circuits has come primarily
from probing their activity in dissected, anesthetized, or restrained animals. However, the …

Animals move through their environments by selecting gaits that are adapted to the physical
nature of their surroundings. The nematode Caenorhabditis elegans swims through fluids or …