Establishment and characterization of a neuroendocrine skin carcinoma cell line.
ST Rosen, VE Gould, HR Salwen, CV Herst… - … ; a journal of technical …, 1987 - europepmc.org
A neuroendocrine skin carcinoma cell line MKL-1 has been established from a nodal metastasis
in a 26-year-old patient. The line grows as irregularly outlined, loosely packed floating …
in a 26-year-old patient. The line grows as irregularly outlined, loosely packed floating …
[HTML][HTML] An effective CTL peptide vaccine for Ebola Zaire Based on Survivors' CD8+ targeting of a particular nucleocapsid protein epitope with potential implications …
The 2013–2016 West Africa EBOV epidemic was the biggest EBOV outbreak to date. An
analysis of virus-specific CD8+ T-cell immunity in 30 survivors showed that 26 of those …
analysis of virus-specific CD8+ T-cell immunity in 30 survivors showed that 26 of those …
Prolonged N-myc protein half-life in a neuroblastoma cell line lacking N-myc amplification.
…, MW Quasney, N Ikegaki, JM Cowan, CV Herst… - Oncogene, 1990 - europepmc.org
Genomic amplification of the oncogene N-myc is associated with rapid tumor progression
and poor prognosis in patients with neuroblastoma (NB). However, 40% of NBs which lack N-…
and poor prognosis in patients with neuroblastoma (NB). However, 40% of NBs which lack N-…
[HTML][HTML] A synthetic peptide CTL vaccine targeting nucleocapsid confers protection from SARS-CoV-2 challenge in rhesus macaques
PE Harris, T Brasel, C Massey, CV Herst, S Burkholz… - Vaccines, 2021 - mdpi.com
Background: Persistent transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has given rise to a COVID-19 pandemic. Several vaccines, conceived in 2020, …
has given rise to a COVID-19 pandemic. Several vaccines, conceived in 2020, …
[HTML][HTML] Paired SARS-CoV-2 spike protein mutations observed during ongoing SARS-CoV-2 viral transfer from humans to minks and back to humans
…, T Hodge, P Harris, S Ciotlos, L Wang, CV Herst… - Infection, Genetics and …, 2021 - Elsevier
A mutation analysis of SARS-CoV-2 genomes collected around the world sorted by sequence,
date, geographic location, and species has revealed a large number of variants from the …
date, geographic location, and species has revealed a large number of variants from the …
Characterization of a novel myeloma cell line, MM. 1
…, HR Salwen, CV Herst… - The Journal of …, 1989 - translationalres.com
A myeloma cell line, MM.1, has been established from the peripheral blood cells of a patient
with immunoglobulin A myeloma. MM.1 grows in suspension either singly or in small …
with immunoglobulin A myeloma. MM.1 grows in suspension either singly or in small …
The place of the bioisosteric sila-substitution in drug design
…, AV Hoonacker, CV Herst - Drug Design Reviews …, 2005 - ingentaconnect.com
Drug design is a complex process that requires a good command of several disciplines
including organic and physical chemistry, biochemistry and metabolism, pharmacology, …
including organic and physical chemistry, biochemistry and metabolism, pharmacology, …
[HTML][HTML] Survivin expression in luminal breast cancer and adjacent normal tissue for immuno-oncology applications
…, PE Harris, T Blankenberg, CV Herst… - International Journal of …, 2023 - mdpi.com
Survivin (BIRC5) is a tumor-associated antigen (TAA) overexpressed in various tumors but
present at low to undetectable levels in normal tissue. Survivin is known to have a high …
present at low to undetectable levels in normal tissue. Survivin is known to have a high …
[HTML][HTML] Eliciting cytotoxic T-lymphocyte responses from synthetic vectors containing one or two epitopes in a C57BL/6 mouse model using peptide-containing …
RM Rubsamen, CV Herst, PM Lloyd, DE Heckerman - Vaccine, 2014 - Elsevier
We describe a vaccine delivery mechanism consisting of a synthetic, non-living vector of
large d,l poly(lactic-co-glycolic) acid (PLGA) microspheres that carry specific cytotoxic T …
large d,l poly(lactic-co-glycolic) acid (PLGA) microspheres that carry specific cytotoxic T …
[HTML][HTML] An approach for a synthetic CTL vaccine design against Zika flavivirus using class I and class II epitopes identified by computer modeling
…, T Olson, A Morrow, S Ciotlos, CV Herst… - Frontiers in …, 2017 - frontiersin.org
The threat posed by severe congenital abnormalities related to Zika virus (ZKV) infection
during pregnancy has turned development of a ZKV vaccine into an emergency. Recent work …
during pregnancy has turned development of a ZKV vaccine into an emergency. Recent work …