Functional amyloids: Where supramolecular amyloid assembly controls biological activity or generates new functionality

JA Buchanan, NR Varghese, CL Johnston… - Journal of Molecular …, 2023 - Elsevier
Functional amyloids are a rapidly expanding class of fibrillar protein structures, with a core
cross-β scaffold, where novel and advantageous biological function is generated by the …

Using single-molecule approaches to understand the molecular mechanisms of heat-shock protein chaperone function

CL Johnston, NR Marzano, AM van Oijen… - Journal of molecular …, 2018 - Elsevier
The heat-shock proteins (Hsp) are a family of molecular chaperones, which collectively form
a network that is critical for the maintenance of protein homeostasis. Traditional ensemble-…

Community-based HIV and STI prevention in women working in indoor sex markets

…, S Thindal, VP Remple, CL Johnston… - Health promotion …, 2013 - journals.sagepub.com
Community research into women’s experiences in the indoor commercial sex industry
illustrated an urgent need for sexually transmitted infection (STI) and HIV education, prevention, …

An α-cyanostilbene derivative for the enhanced detection and imaging of amyloid fibril aggregates

NR Marzano, KM Wray, CL Johnston… - ACS Chemical …, 2020 - ACS Publications
The aggregation of proteins into amyloid fibrils has been implicated in the pathogenesis of a
variety of neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s …

[HTML][HTML] Single-molecule fluorescence-based approach reveals novel mechanistic insights into human small heat shock protein chaperone function

CL Johnston, NR Marzano, BP Paudel, G Wright… - Journal of Biological …, 2021 - ASBMB
Small heat shock proteins (sHsps) are a family of ubiquitous intracellular molecular chaperones;
some sHsp family members are upregulated under stress conditions and play a vital …

Offer of financial incentives for unprotected sex in the context of sex work

CL Johnston, C Callon, K Li, E Wood… - Drug and alcohol …, 2010 - Wiley Online Library
Introduction and Aims. Commercial sex workers (CSW) are often portrayed as vectors of
disease transmission. However, the role clients play in sexual risk taking and related decision …

Surface-Induced Hydrophobin Assemblies with Versatile Properties and Distinct Underlying Structures

R Siddiquee, V Lo, CL Johnston, AW Buffier… - …, 2023 - ACS Publications
Hydrophobins are remarkable proteins due to their ability to self-assemble into amphipathic
coatings that reverse surface wettability. Here, the versatility of the Class I hydrophobins …

Single-molecule fluorescence-based approach reveals novel mechanistic insights into small heat shock protein chaperone function

CL Johnston, NR Marzano, B Paudel, G Wright… - bioRxiv, 2020 - biorxiv.org
Small heat shock proteins (sHsps) are a family of ubiquitous intracellular molecular chaperones
that are up-regulated under stress conditions and play a vital role in protein homeostasis …

Supporting indoor commercial sex worker's (CSW) access to HIV/STI services.

CL Johnston - 2009 - summit.sfu.ca
Background: Indoor CSW are at high risk for HIV/STI. They are invisible to the public and
often ignored by service and research. Many CSW in Vancouver are migrant therefore it is …

[HTML][HTML] Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: a pilot study of 10 patients with major depression and …

F Schiffer, AL Johnston, C Ravichandran… - Behavioral and brain …, 2009 - Springer
Background Many studies have reported beneficial effects from the application of near-infrared
(NIR) light photobiomodulation (PBM) to the body, and one group has reported beneficial …