The Transatlantic Slave Trade transported more than 9 million Africans to the Americas between
the early 16th and the mid-19th centuries. We performed a genome-wide analysis using …

Western South America was one of the worldwide cradles of civilization. The well-known Inca
Empire was the tip of the iceberg of an evolutionary process that started 11,000 to 14,000 …

We present allele frequencies involving 39 pharmacogenetic biomarkers studied in Brazil,
and their distribution on self-reported race/color categories that: (1) involve a mix of …

The COVID-19 pandemic has created an unprecedented need for epidemiological monitoring
using diverse strategies. We conducted a project combining prevalence, seroprevalence, …

EPIGEN-Brazil is one of the largest Latin American initiatives at the interface of human
genomics, public health, and computational biology. Here, we present two resources to address …

Genetic and omics analyses frequently require independent observations, which is not
guaranteed in real datasets. When relatedness cannot be accounted for, solutions involve …

Background Gastric adenocarcinoma is associated with chronic infection by Helicobacter
pylori and with the host inflammatory response triggered by it, with substantial inter-person …

For human/SARS-CoV-2 interactome genes ACE2, TMPRSS2 and BSG, there is a
convincing evidence of association in Asians with influenza-induced SARS for TMPRSS2-rs2070788, …

PDE4B (phosphodiesterase‐4B) has an important role in cancer and in pharmacology of
some disorders, such as inflammatory diseases. Remarkably in Native Americans, PDE4B …

Background/objectives Admixed populations are a resource to study the global genetic
architecture of complex phenotypes, which is critical, considering that non-European populations …