Evaluation of the diagnostic utility of cytologic examination of renal fine-needle aspirates from dogs and the use of ultrasonographic features to inform cytologic …

CA McAloney, LC Sharkey, DA Feeney… - Journal of the …, 2018 - Am Vet Med Assoc
OBJECTIVE To describe cytologic characteristics of renal fine-needle aspirate (FNA)
samples from dogs, evaluate proportions of cytologic specimens deemed adequate for …

[HTML][HTML] Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization

CA McAloney, R Makkawi, Y Budhathoki, MV Cannon… - Cellular Oncology, 2023 - Springer
Purpose For patients with osteosarcoma, disease-related mortality most often results from
lung metastasis—a phenomenon shared with many solid tumors. While established metastatic …

Comparison of pathologist review protocols for cytologic detection of prostatic and urothelial carcinomas in canines: A bi‐institutional retrospective study of 298 cases

CA McAloney, SJM Evans, JA Hokamp… - Veterinary and …, 2021 - Wiley Online Library
Urothelial carcinoma, also known as transitional cell carcinoma, is the most common primary
bladder tumour in dogs, and can also involve the prostate gland. Cytology is a common …

[HTML][HTML] Polymorphisms within the Telomerase Reverse Transcriptase gene (TERT) in four breeds of dogs selected for difference in lifespan and cancer susceptibility

CA McAloney, KAT Silverstein, JF Modiano… - BMC veterinary …, 2014 - Springer
Background Enzymatic activity of Telomerase Reverse Transcriptase (TERT) is important in
maintaining the telomere length and has been implicated in cancer and aging related …

Diagnostic utility of renal fine-needle aspirate cytology and ultrasound in the cat

CA McAloney, LC Sharkey… - Journal of feline …, 2018 - journals.sagepub.com
Objectives The primary objective of this study was to retrospectively assess the diagnostic
utility of feline renal fine-needle aspiration cytology by assessing diagnostic yield, cytologic …

[HTML][HTML] Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization

S Rajan, EM Franz, CA McAloney, TA Vetter, M Cam… - BMC biology, 2023 - Springer
Background Tumors are complex tissues containing collections of phenotypically diverse
malignant and nonmalignant cells. We know little of the mechanisms that govern heterogeneity …

Ectodomain shedding by ADAM17 (a disintegrin and metalloproteinase 17) in canine neutrophils

KM Snyder, CA McAloney, JS Montel… - Veterinary immunology …, 2021 - Elsevier
ADAM17 is a transmembrane protease expressed by most cells in humans and mice that
cleaves cell surface substrates primarily in a cis manner, a process referred to as ectodomain …

Nasal colonization by Entamoeba gingivalis in a 13‐year‐old Italian Greyhound

NK Randolph, CA McAloney, R Ossiboff… - Veterinary Clinical …, 2022 - Wiley Online Library
A 13‐year‐old 4.6 kg castrated male Italian Greyhound was presented for evaluation of
sneezing, bilateral epistaxis and mucoid nasal discharge of approximately 3 months duration. …

Gastrointestinal colonization by Diutina (Candida) rugosa in a 6‐year‐old Siberian Husky

NK Randolph, J Her, CA McAloney… - Veterinary Clinical …, 2024 - Wiley Online Library
A 6‐year‐old 21.5 kg castrated male Siberian Husky was presented for acute onset of
lethargy, vomiting, hemorrhagic diarrhea, and inappetence. Physical examination revealed …

MAPK-driven MCL1 expression promotes osteosarcoma survival in the metastatic niche

CA McAloney, R Makkawi, MV Cannon, AC Gross… - Cancer Research, 2023 - AACR
We sought to identify dependencies of slow growing, chemo-resistant osteosarcoma cells
that anchor in the metastatic niche. These dependencies yield insight into what allows early …