BMP signaling plays key roles in development, stem cells, adult tissue homeostasis, and
disease. How BMP receptors are extracellularly modulated and in which physiological context, …

Lung cancer is one of the deadliest cancers worldwide. Late diagnosis at an advanced,
inoperable stage makes chemotherapy a treatment of choice, yet, with low response rates. The …

WNT signaling is important in development, stem cell maintenance, and disease. WNT
ligands typically signal via receptor activation across the plasma membrane to induce β-catenin-…

It is widely thought that Wnt/Lrp6 signaling proceeds through the cytoplasm and that motile
cilia are signaling-inert nanomotors. Contrasting both views, we here show in the mucociliary …

The human gastrointestinal tract (GIT) is the primary site of nutrient absorption, as well as a
crucial barrier against xenobiotics. It regularly faces “chemical cocktails” composed of food …

WNT signalling is of paramount importance in development, stem cell maintenance, and
disease. WNT ligands typically signal via receptor activation at the plasma membrane to induce …

BMP signalling plays key roles in development, stem cells, adult tissue homeostasis, and
disease. How BMP receptors are extracellularly modulated and in which physiological context, …

Lung cancer is a leading cause of cancer deaths worldwide and platinum-based chemotherapy
(eg cisplatin) is frequently the treatment of choice. However, resistance to cisplatin is a …

Background BMP-induced chemotaxis of mesenchymal progenitors is fundamental for vertebrate
development, disease and tissue repair. BMP2 induces Smad and non-Smad signalling…

… All iatrogenic injuries to the trachea between the cricoid cartilage and the level of the carina
… injury between the cricoid cartilage and the carina. The study recorded personal details, …