[PDF][PDF] Odilorhabdins, antibacterial agents that cause miscoding by binding at a new ribosomal site
…, C Cotteaux-Lautard, JM Bolla, CV Lundberg… - Molecular cell, 2018 - cell.com
Growing resistance of pathogenic bacteria and shortage of antibiotic discovery platforms
challenge the use of antibiotics in the clinic. This threat calls for exploration of unconventional …
challenge the use of antibiotics in the clinic. This threat calls for exploration of unconventional …
Quality and vaccine efficacy of CD4+ T cell responses directed to dominant and subdominant epitopes in ESAT-6 from Mycobacterium tuberculosis
…, TTKT Hoang, C Vingsbo-Lundberg… - The Journal of …, 2009 - journals.aai.org
The ESAT-6 (early secretory antigenic target) molecule is a very important target for T cell
recognition during infection with Mycobacterium tuberculosis. Although ESAT-6 contains …
recognition during infection with Mycobacterium tuberculosis. Although ESAT-6 contains …
[HTML][HTML] Genetic control of arthritis onset, severity and chronicity in a model for rheumatoid arthritis in rats
C Vingsbo-Lundberg, N Nordquist, P Olofsson… - Nature …, 1998 - nature.com
Rheumatoid arthritis (RA) is a chronic and genetically complex inflammatory disorder that
leads to erosive destruction of peripheral joints 1, 2, 3, 4, 5. The use of animal models …
leads to erosive destruction of peripheral joints 1, 2, 3, 4, 5. The use of animal models …
Induction of CD8 T cells against a novel epitope in TB10. 4: correlation with mycobacterial virulence and the presence of a functional region of difference-1
R Billeskov, C Vingsbo-Lundberg… - The Journal of …, 2007 - journals.aai.org
Although infection with Mycobacterium tuberculosis (M. tb) induces a robust CD8 T cell
response, the role of CD8 T cells in the defense against M. tb, and the mechanisms behind the …
response, the role of CD8 T cells in the defense against M. tb, and the mechanisms behind the …
[HTML][HTML] ESAT-6 (EsxA) and TB10. 4 (EsxH) based vaccines for pre-and post-exposure tuberculosis vaccination
…, JP Cassidy, G Dolganov, GK Schoolnik, CV Lundberg… - PloS one, 2013 - journals.plos.org
The ESX systems from Mycobacterium tuberculosis are responsible for the secretion of
highly immunogenic proteins of key importance for bacterial survival and growth. The two …
highly immunogenic proteins of key importance for bacterial survival and growth. The two …
[HTML][HTML] An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria
Peptide antibiotics are an abundant and synthetically tractable source of molecular diversity,
but they are often cationic and can be cytotoxic, nephrotoxic and/or ototoxic, which has …
but they are often cationic and can be cytotoxic, nephrotoxic and/or ototoxic, which has …
Genomic identification of cryptic susceptibility to penicillins and β-lactamase inhibitors in methicillin-resistant Staphylococcus aureus
…, J Larsen, A Rhod Larsen, C Vingsbo Lundberg… - Nature …, 2019 - nature.com
Antibiotic resistance in bacterial pathogens threatens the future of modern medicine. One
such resistant pathogen is methicillin-resistant Staphylococcus aureus (MRSA), which is …
such resistant pathogen is methicillin-resistant Staphylococcus aureus (MRSA), which is …
Enhanced humoral and cell-mediated immune responses after immunization with trivalent influenza vaccine adjuvanted with cationic liposomes
I Rosenkrands, C Vingsbo-Lundberg, TJ Bundgaard… - Vaccine, 2011 - Elsevier
The recent pandemic caused by new influenza A (H1N1) has emphasized the need for
improved influenza vaccines with enhanced immune responses that ideally include longlived …
improved influenza vaccines with enhanced immune responses that ideally include longlived …
Model‐informed drug development for antimicrobials: translational PK and PK/PD modeling to predict an efficacious human dose for apramycin
…, D Zabicka, C Vingsbo Lundberg… - Clinical …, 2021 - Wiley Online Library
Apramycin represents a subclass of aminoglycoside antibiotics that has been shown to
evade almost all mechanisms of clinically relevant aminoglycoside resistance. Model‐informed …
evade almost all mechanisms of clinically relevant aminoglycoside resistance. Model‐informed …
Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a …
…, L Guardabassi, J Pace, CV Lundberg… - Clinical and …, 2022 - Wiley Online Library
Background In patients with atopic dermatitis (AD), Staphylococcus aureus frequently
colonizes lesions and is hypothesized to be linked to disease severity and progression. …
colonizes lesions and is hypothesized to be linked to disease severity and progression. …