Mechanotransduction - how cells sense physical forces and translate them into biochemical
and biological responses - is a vibrant and rapidly-progressing field, and is important for a …

A reliable extraction of filament data from microscopic images is of high interest in the
analysis of acto-myosin structures as early morphological markers in mechanically guided …

Despite recent efforts to understand homeostasis in epithelial tissues, there are many unknowns
surrounding this steady state. It is considered to be regulated by mechanoresponse, but …

We report a novel method, dual-color axial nanometric localization by metal-induced energy
transfer, and combine it with Förster resonance energy transfer (FRET) for resolving …

Adult human mesenchymal stem cells show structural rearrangements of their cytoskeletal
network during mechanically induced differentiation toward various cell types. In particular, …

We generalize the SiZer of Chaudhuri and Marron (J. Amer. Statist. Assoc. 94 (1999) 807–823;
Ann. Statist. 28 (2000) 408–428) for the detection of shape parameters of densities on the …

Kidney fibrosis presents a hallmark of chronic kidney disease. With ever-increasing patient
numbers and limited treatment options available, novel strategies for therapeutic intervention …

Mutations in the lysosomal membrane protein CLN3 cause Juvenile Neuronal Ceroid
Lipofuscinosis (JNCL). Activation of the lysosomal ion channel TRPML1 has previously been …

Despite the primary role of cell proliferation in tissue development and homeostatic maintenance,
the interplay between cell density, cell mechanoresponse, and cell growth and division …

The paper deals with modeling of segment systems in a bounded planar set (a cell) by
means of random segment processes. Two models with a density with respect to the Poisson …