Hsl7 localizes to a septin ring and serves as an adapter in a regulatory pathway that relieves tyrosine phosphorylation of Cdc28 protein kinase in Saccharomyces …

MJ Shulewitz, CJ Inouye, J Thorner - Molecular and Cellular …, 1999 - Taylor & Francis
Successful mitosis requires faithful DNA replication, spindle assembly, chromosome
segregation, and cell division. In the budding yeast Saccharomyces cerevisiae, the G 2 -to-M …

Determining cellular CTCF and cohesin abundances to constrain 3D genome models

…, CJ Inouye, MJ Hossain, GM Dailey, J Ellenberg… - Elife, 2019 - elifesciences.org
10.7554/eLife.40164.001 Achieving a quantitative and predictive understanding of 3D genome
architecture remains a major challenge, as it requires quantitative measurements of the …

Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae

L Bardwell, JG Cook, CJ Inouye, J Thorner - Developmental biology, 1994 - Elsevier
Extracellular signals can affect the rate of proliferation and the state of differentiation of eukaryotic
cells. Signal transduction pathways have evolved to detect these signals at the plasma …

[HTML][HTML] Cyclophilin A and FKBP12 Interact with YY1 and Alter Its Transcriptional Activity (∗)

WM Yang, CJ Inouye, E Seto - Journal of Biological Chemistry, 1995 - ASBMB
YY1 is a zinc finger transcription factor with unusual structural and functional features. In a
yeast two-hybrid screen, two cellular proteins, cyclophilin A (CyPA) and FK506-binding …

Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 …

C Sette, CJ Inouye, SL Stroschein… - Molecular biology of …, 2000 - Am Soc Cell Biol
Ste5 is essential for pheromone response and binds components of a mitogen-activated
protein kinase (MAPK) cascade: Ste11 (MEKK), Ste7 (MEK), and Fus3 (MAPK). Pheromone …

[PDF][PDF] Architectural Features of 3D Genome Organization Revealed by Counting CTCF and Cohesin Molecules

C Cattoglio, I Pustova, JJ Ho, CJ Inouye, GM Dailey… - BioRxiv, 2018 - researchgate.net
Achieving a quantitative and predictive understanding of 3D genome architecture presents
a major challenge and aspiration. However, this milestone will not be achieved without …

[HTML][HTML] Relief of YY1-induced transcriptional repression by protein-protein interaction with the nucleolar phosphoprotein B23.

CJ Inouye, E Seto - Journal of Biological Chemistry, 1994 - Elsevier
… While promoter activity was modulated as much as 1000-fold byElA, the observed
effectby CJ Inouye and E. Seto, unpublished results. - - + - + 65 10 REFERENCES YYl -B23 …

Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3

WM Yang, C Inouye, Y Zeng… - Proceedings of the …, 1996 - National Acad Sciences
YY1 is a mammalian zinc-finger transcription factor with unusual structural and functional
features. It has been implicated as a positive and a negative regulatory factor that binds to the …

Selectivity of chromatin-remodelling cofactors for ligand-activated transcription

B Lemon, C Inouye, DS King, R Tjian - Nature, 2001 - nature.com
An array of regulatory protein and multi-subunit cofactors has been identified 1 that directs
eukaryotic gene transcription. However, establishing the specific functions of various related …

Ste5 RING-H2 domain: role in Ste4-promoted oligomerization for yeast pheromone signaling

C Inouye, N Dhillon, J Thorner - Science, 1997 - science.org
Ste5 is a scaffold for the mitogen-activated protein kinase (MAPK) cascade components in a
yeast pheromone response pathway. Ste5 also associates with Ste4, the β subunit of a …