Pathological hallmarks of Alzheimer’s disease (AD) precede clinical symptoms by years,
indicating a period of cognitive resilience before the onset of dementia. Here, we report that …

Background The pathogenic road map leading to Alzheimer's disease (AD) is still not
completely understood; however, a large body of studies in the last few years supports the idea …

Prior studies suggested that the transcription factor ATF4 negatively regulates synaptic plastic
and memory. By contrast, we provide evidence from direct in vitro and in vivo knockdown …

Oligomeric Amyloid β 1–42 (Aβ) plays a crucial synaptotoxic role in Alzheimer’s disease,
and hyperphosphorylated tau facilitates Aβ toxicity. The link between Aβ and tau, however, …

Intermittent fasting (IF) is a diet with salutary effects on cognitive aging, Alzheimer's disease (AD),
and stroke. IF restricts a number of nutrient components, including glucose. 2-…

Amyloid-β (Aβ) deposition and tau-dependent pathology are key features of Alzheimer's
disease (AD). However, to date, approaches aimed at counteracting these two pathogenic …

Background Undergraduate research experiences (UREs) have been proposed as means
to increase the retention and engagement of minority—and more specifically Hispanic—…

Firm-specific information can affect expected returns if it affects investor uncertainty about
risk-factor loadings. We show that a stock's expected return is decreasing in factor-loading …

Converging lines of inquiry have highlighted the importance of the Type I antiviral response
not only in defending against viruses but also in preconditioning the brain against ischaemic …

Activating Transcription Factor 4 (ATF4) has been postulated as a key regulator of learning
and memory. We previously reported that specific hippocampal ATF4 downregulation causes …