[HTML][HTML] The endogenous cellular protease inhibitor SPINT2 controls SARS-CoV-2 viral infection and is associated to disease severity

C Ramirez Alvarez, C Kee, AK Sharma… - PLoS …, 2021 - journals.plos.org
COVID-19 outbreak is the biggest threat to human health in recent history. Currently, there
are over 1.5 million related deaths and 75 million people infected around the world (as of 22/…

SPINT2 controls SARS-CoV-2 viral infection and is associated to disease severity

CR Alvarez, AK Sharma, C Kee, L Thomas, S Boulant… - bioRxiv, 2020 - biorxiv.org
COVID-19 outbreak is the biggest threat to human health in recent history. Currently, there
are over 1.5 million related deaths and 75 million people infected around the world (as of 22/…

[HTML][HTML] Analytical validation of quantitative real-time PCR methods for quantification of Trypanosoma cruzi DNA in blood samples from Chagas disease patients

JC Ramírez, CI Cura, O da Cruz Moreira… - The Journal of Molecular …, 2015 - Elsevier
An international study was performed by 26 experienced PCR laboratories from 14 countries
to assess the performance of duplex quantitative real-time PCR (qPCR) strategies on the …

New scheme of intermittent benznidazole administration in patients chronically infected with Trypanosoma cruzi: a pilot short-term follow-up study with adult patients

…, M Fernández, B Lococo, JC Ramírez… - Antimicrobial agents …, 2016 - Am Soc Microbiol
There is a clinical need to test new schemes of benznidazole administration that are expected
to be at least as effective as the current therapeutic scheme but safer. This study assessed …

New scheme of intermittent benznidazole administration in patients chronically infected with Trypanosoma cruzi: clinical, parasitological, and serological assessment …

MG Álvarez, JC Ramírez, G Bertocchi… - Antimicrobial agents …, 2020 - Am Soc Microbiol
In a pilot study, we showed that the intermittent administration of benznidazole in chronic
Chagas disease patients resulted in a low rate of treatment suspension and therapeutic failure, …

Dengue and hepatic failure

ME Alvarez, CH Ramírez-Ronda - The American journal of medicine, 1985 - Elsevier
Dengue hemorrhagic fever/dengue shock syndrome is a serious manifestation of dengue
fever, which is observed predominantly in the tropical regions of the West Pacific and in …

Sulfmyoglobin production by free cysteine during thermal treatment: Involvement of heme iron in the production of free radicals

…, G García-Sánchez, JC Ramírez-Suárez - Food Chemistry, 2023 - Elsevier
The meat greening is an abnormal pigmentation related to microbiological contamination
and lipid oxidation during storage. This color change results from sulfmyoglobin (SulfMb) …

Characterizing neurological disease from voice quality biomechanical analysis

…, A Álvarez-Marquina, C Ramírez-Calvo… - Cognitive …, 2013 - Springer
The dramatic impact of neurological degenerative pathologies in life quality is a growing
concern nowadays. Many techniques have been designed for the detection, diagnosis, and …

Review of the Greening Reaction by Thermal Treatment: New Insights Exploring the Structural Implications of Myoglobin

…, JC Ramírez-Suárez - Journal of Agricultural …, 2023 - ACS Publications
Myoglobin is the main factor responsible for muscle pigmentation in tuna; muscle color
depends upon changes in the oxidative state of myoglobin. The tuna industry has reported …

Hematologic β-tubulin VI isoform exhibits genetic variability that influences paclitaxel toxicity

…, Á Gómez-Graña, R Torres, JC Ramírez, S Álvarez… - Cancer research, 2012 - AACR
Cellular microtubules composed of α-β-tubulin heterodimers that are essential for cell shape,
division, and intracellular transport are valid targets for anticancer therapy. However, not all …