Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

…, D Braeken, G Callewaert, C Bartic… - The EMBO …, 2010 - embopress.org
The amyloid peptides Aβ 40 and Aβ 42 of Alzheimer's disease are thought to contribute
differentially to the disease process. Although Aβ 42 seems more pathogenic than Aβ 40 , the …

An implantable 455-active-electrode 52-channel CMOS neural probe

…, M Welkenhuysen, W Eberle, C Bartic… - IEEE Journal of Solid …, 2013 - ieeexplore.ieee.org
Neural probes have become the most important tool for enabling neuroscientists to place
microelectrode sensors close to individual neurons and to monitor their activity in vivo. With …

Organic thin-film transistors as transducers for (bio) analytical applications

C Bartic, G Borghs - Analytical and bioanalytical chemistry, 2006 - Springer
The use of organic thin-film transistors (OTFTs) in sensorics is relatively new. Although
electronic noses, electronic textiles and disposable biochemical sensors appear to be viable …

Field-effect detection of chemical species with hybrid organic/inorganic transistors

C Bartic, A Campitelli, S Borghs - Applied Physics Letters, 2003 - pubs.aip.org
In this letter, we demonstrate that organic-based transistors are able to detect charged/uncharged
chemical species in aqueous media via the field effect. The chemical sensitivity of the …

Spine-shaped gold protrusions improve the adherence and electrical coupling of neurons with the surface of micro-electronic devices

…, J Shappir, S Yitzchaik, C Bartic… - Journal of The …, 2009 - royalsocietypublishing.org
Interfacing neurons with micro- and nano-electronic devices has been a subject of intense
study over the last decade. One of the major problems in assembling efficient neuro-electronic …

Monitoring pH with organic-based field-effect transistors

C Bartic, B Palan, A Campitelli, G Borghs - Sensors and Actuators B …, 2002 - Elsevier
In this paper we propose a simple device and a method for pH monitoring, using an organic
thin-film transistor as transducer. Such organic transducers may show potential advantages …

[HTML][HTML] The Alzheimer disease protective mutation A2T modulates kinetic and thermodynamic properties of amyloid-β (Aβ) aggregation

…, VC Cano, A Snellinx, M Ramakers, C Bartic… - Journal of Biological …, 2014 - ASBMB
Missense mutations in alanine 673 of the amyloid precursor protein (APP), which corresponds
to the second alanine of the amyloid β (Aβ) sequence, have dramatic impact on the risk …

Ta2O5 as gate dielectric material for low-voltage organic thin-film transistors

C Bartic, H Jansen, A Campitelli, S Borghs - Organic electronics, 2002 - Elsevier
In this paper we report the use of Ta 2 O 5 as gate dielectric material for organic thin-film
transistors. Ta 2 O 5 has already attracted a lot of attention as insulating material for VLSI …

Single-cell recording and stimulation with a 16k micro-nail electrode array integrated on a 0.18 μm CMOS chip

…, F Vleugels, G Callewaert, K Verstreken, C Bartic… - Lab on a Chip, 2012 - pubs.rsc.org
To cope with the growing needs in research towards the understanding of cellular function
and network dynamics, advanced micro-electrode arrays (MEAs) based on integrated …

[HTML][HTML] Substrate Topography Determines Neuronal Polarization and Growth In Vitro

…, A Gärtner, D Prodanov, D Braeken, CG Dotti, C Bartic - PloS one, 2013 - journals.plos.org
The establishment of neuronal connectivity depends on the correct initial polarization of the
young neurons. In vivo, developing neurons sense a multitude of inputs and a great number …