Celiac disease is caused by an abnormal intestinal T-cell response to gluten proteins of
wheat, barley and rye. Over the last few years, a number of gluten T-cell epitopes restricted by …

Celiac disease is a genetic condition that results in a debilitating immune reaction in the gut
to antigens in grain. The antigenic peptides recognized by the T cells that cause this disease …

Presently, the only effective treatment for celiac disease is a life-long gluten-free diet. In this
work, we used a new mixture of selected sourdough lactobacilli and fungal proteases to …

Class I restricted cytotoxic T-lymphocyte (CTL) responses are thought to be focused against
few immunodominant epitopes. In humans, an often quoted example of such narrow focus is …

One of the diagnostic hallmarks of the histological lesions associated with celiac disease is
the extensive infiltration of the small intestinal epithelium by CD8+ T cells of unknown Ag …

The identification of gluten peptides eliciting intestinal T cell responses is crucial for the
design of a peptide-based immunotherapy in celiac disease (CD). To date, several gluten …

The gluten-free diet is, to date, the only efficacious treatment for patients with Celiac Disease.
In recent years, the impressive rise of Celiac Disease incidence, dramatically prompted …

Celiac disease (CD) is a complex small intestinal disorder due to a dysregulated immune
response to wheat gliadin and related proteins which leads to a small intestinal enteropathy. It …

Background & Aims: Celiac disease is characterized by activation of HLA-DQ2/DQ8–restricted
intestinal gluten-specific CD4 + T cells. In particular, gluten becomes a better T-cell …

Celiac disease is caused by an abnormal intestinal T cell response to cereal gluten proteins.
The disease has a strong human leukocyte antigen (HLA) association, and CD4 + T cells …