User profiles for Carol Gilchrist

Carol A. Gilchrist

University of Virginia
Verified email at virginia.edu
Cited by 3987

[HTML][HTML] The genome of the protist parasite Entamoeba histolytica

…, H Norbertczak, C Price, Z Wang, N Guillén, C Gilchrist… - Nature, 2005 - nature.com
Entamoeba histolytica is an intestinal parasite and the causative agent of amoebiasis, which
is a significant source of morbidity and mortality in developing countries 1 . Here we present …

Whole-genome sequencing in outbreak analysis

CA Gilchrist, SD Turner, MF Riley… - Clinical microbiology …, 2015 - Am Soc Microbiol
In addition to the ever-present concern of medical professionals about epidemics of
infectious diseases, the relative ease of access and low cost of obtaining, producing, and …

Impact of intestinal colonization and invasion on the Entamoeba histolytica transcriptome

CA Gilchrist, E Houpt, N Trapaidze, Z Fei… - Molecular and …, 2006 - Elsevier
A genome-wide transcriptional analysis of Entamoeba histolytica was performed on
trophozoites isolated from the colon of six infected mice and from in vitro culture. An Affymetrix …

[HTML][HTML] A mutation in the leptin receptor is associated with Entamoeba histolytica infection in children

…, RL Leibel, E Houpt, CA Gilchrist… - The Journal of …, 2011 - Am Soc Clin Investig
Malnutrition substantially increases susceptibility to Entamoeba histolytica in children.
Leptin is a hormone produced by adipocytes that inhibits food intake, influences the immune …

Role of the Gut Microbiota of Children in Diarrhea Due to the Protozoan Parasite Entamoeba histolytica

CA Gilchrist, SE Petri, BN Schneider… - The Journal of …, 2016 - academic.oup.com
Background. An estimated 1 million children die each year before their fifth birthday from
diarrhea. Previous population-based surveys of pediatric diarrheal diseases have identified the …

Parasitic protozoa and interactions with the host intestinal microbiota

SL Burgess, CA Gilchrist, TC Lynn… - Infection and …, 2017 - Am Soc Microbiol
Parasitic protozoan infections represent a major health burden in the developing world and
contribute significantly to morbidity and mortality. These infections are often associated with …

[HTML][HTML] Natural history of cryptosporidiosis in a longitudinal study of slum-dwelling Bangladeshi children: association with severe malnutrition

PS Korpe, R Haque, C Gilchrist… - PLoS neglected …, 2016 - journals.plos.org
Background Cryptosporidiosis is a common cause of infectious diarrhea in young children
worldwide, and is a significant contributor to under-five mortality. Current treatment options …

[HTML][HTML] Specific Cryptosporidium antigens associate with reinfection immunity and protection from cryptosporidiosis

CA Gilchrist, JJ Campo, JV Pablo… - The Journal of …, 2023 - Am Soc Clin Investig
There is no vaccine to protect from cryptosporidiosis, a leading cause of diarrhea in infants
in low- and middle-income countries. Here, we comprehensively identified parasite antigens …

Entamoeba histolytica: genetic diversity of clinical isolates from Bangladesh as demonstrated by polymorphisms in the serine-rich gene

PF Ayeh-Kumi, IM Ali, LA Lockhart, CA Gilchrist… - Experimental …, 2001 - Elsevier
Ayeh-Kumi, PF, Ali, IM, Lockhart, LA, Gilchrist, CA, Petri, WA, Jr., and Hague, R. 2001.
Entamoeba histolytica: Genetic diversity of clinical isolates from Bangladesh as demonstrated by …

[HTML][HTML] Microbiome-mediated neutrophil recruitment via CXCR2 and protection from amebic colitis

K Watanabe, CA Gilchrist, MJ Uddin, SL Burgess… - PLoS …, 2017 - journals.plos.org
The disease severity of Entamoeba histolytica infection ranges from asymptomatic to life-threatening.
Recent human and animal data implicate the gut microbiome as a modifier of E. …