Background: Malignant gastrointestinal stromal tumors (M-GIST) are rare mesenchymal
tumors originating in the wall of the gastrointestinal (GI) tract. Previous studies have included …

To evaluate histologic subtype and grade, which in turn guide the decision making for
multimodality therapy, the workup of suspected sarcoma requires more material than can be …

Sak/Plk4 differs from other polo-like kinases in having only a single polo box, which assumes
a novel dimer fold that localizes to the nucleolus, centrosomes and the cleavage furrow. …

Objective: To measure sexual function and quality of life (QOL) after rectal cancer treatment.
Summary Background Data: Previous studies on sexual function after rectal cancer …

Background Unlike for extremity sarcomas, the efficacy of radiotherapy for retroperitoneal
sarcoma is not established. The aim of this study was to evaluate the impact of preoperative …

Background: Retroperitoneal sarcomas (RPS) are rare tumors composed of several well
defined histologic subtypes. The aim of this study was to analyze patterns of recurrence and …

Background The reported data on surgery plus radiotherapy for retroperitoneal soft tissue
sarcomas (RPS) have been mostly from retrospective studies. We evaluated the long-term …

Soluble transforming growth factor-β (TGF-β)/bone morphogenetic protein (BMP)-binding
proteins are widely distributed in mammalian tissues and control cytokine access to membrane …

The polo-like kinase Plk4 (also called Sak) is required for late mitotic progression, cell survival
and postgastrulation embryonic development 1 . Here we identified a phenotype resulting …

Background Retroperitoneal soft tissue sarcomas comprise a heterogeneous group of rare
tumors of mesenchymal origin that include several well-defined histologic subtypes. In 2015, …