As SARS-CoV-2 infections and death counts continue to rise, it remains unclear why some
individuals recover from infection, whereas others rapidly progress and die. Although the …

Neonates are born with an immature immune system and rely on the transfer of immunity
from their mothers. Maternal antibodies are transferred via the placenta and breast milk. …

The relationship between SARS-CoV-2 viral load and risk of disease progression remains
largely undefined in coronavirus disease 2019 (COVID-19). Here, we quantify SARS-CoV-2 …

The global coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has made the development of a vaccine a top …

The development of a portfolio of COVID-19 vaccines to vaccinate the global population
remains an urgent public health imperative 1 . Here we demonstrate the capacity of a subunit …

Background Pregnant and lactating women were excluded from initial coronavirus disease
2019 vaccine trials; thus, data to guide vaccine decision making are lacking. Objective This …

SARS-CoV-2 infection causes more severe disease in pregnant women compared to age-matched
non-pregnant women. Whether maternal infection causes changes in the transfer of …

Recent studies have reported the protective efficacy of both natural 1 and vaccine-induced
2 , 3 , 4 , 5 , 6 – 7 immunity against challenge with severe acute respiratory syndrome …

A safe and effective vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
may be required to end the coronavirus disease 2019 (COVID-19) pandemic 1 , 2 , 3 , 4 …

Antibodies are key immune effectors that confer protection against pathogenic threats. The
nature and longevity of the antibody response to SARS-CoV-2 infection are not well defined. …