CD169+ macrophages are sufficient for priming of CTLs with specificities left out by cross-priming dendritic cells

CA Bernhard, C Ried, S Kochanek… - Proceedings of the …, 2015 - National Acad Sciences
Dendritic cells (DCs) are considered the most potent antigen-presenting cells (APCs), which
directly prime or cross-prime MHC I-restricted cytotoxic T cells (CTLs). However, recent …

[HTML][HTML] MHC class I cross-presentation by dendritic cells counteracts viral immune evasion

K Nopora, CA Bernhard, C Ried, AA Castello… - Frontiers in …, 2012 - frontiersin.org
DCs very potently activate CD8 + T cells specific for viral peptides bound to MHC class I
molecules. However, many viruses have evolved immune evasion mechanisms, which …

[HTML][HTML] Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8+ Dendritic Cells

…, C Ried, L Grosse, C Simon, C Bernhard… - Frontiers in …, 2019 - frontiersin.org
Apoptotic cell death of Dendritic cells (DCs) is critical for immune homeostasis. Although
intrinsic mechanisms controlling DC death have not been fully characterized up to now, …

Comparative analysis of CTL-repertoires induced by different vaccine vectors

CA Bernhard - The Journal of Immunology, 2016 - journals.aai.org
Dendritic cells (DCs) are considered the most potent antigen-presenting cells (APCs), which
directly prime or cross-prime MHCI-restricted cytotoxic T cells (CTLs). Although we know …

Three'sa crowd: 10q triplication secondary to a paternal 10q duplication

A Gardham, C Sullivan, B Bernhard - Clinical Dysmorphology, 2014 - journals.lww.com
Partial chromosome triplications are relatively rare and may be mistaken for duplications
using conventional cytogenetic techniques. Most reported triplications are de novo and many …

[PDF][PDF] Exotic mineralization at Chuquicamata, Chile: focus on the copper wad enigma

M Marie-Caroline Pinget, B Dold, L Fontboté - academia.edu
Supergene processes in porphyry copper deposits are important for their economic potential
(Sillitoe, 2005). Meteoric fluids oxidize the upper part of the sulfidic deposit; oxidation of …

Molecular analysis of CaMnt1p, a mannosyl transferase important for adhesion and virulence of Candida albicans

ET Buurman, C Westwater, B Hube… - Proceedings of the …, 1998 - National Acad Sciences
There is an immediate need for identification of new antifungal targets in opportunistic pathogenic
fungi like Candida albicans. In the past, efforts have focused on synthesis of chitin and …

[HTML][HTML] Real-time cardiovascular magnetic resonance T1 and extracellular volume fraction mapping for tissue characterisation in aortic stenosis

SJ Backhaus, T Lange, BE Beuthner, R Topci… - Journal of …, 2020 - Springer
Background Myocardial fibrosis is a major determinant of outcome in aortic stenosis (AS).
Novel fast real-time (RT) cardiovascular magnetic resonance (CMR) mapping techniques …

Niche differentiation among annually recurrent coastal Marine Group II Euryarchaeota

LH Orellana, TB Francis, K Krüger, H Teeling… - The ISME …, 2019 - academic.oup.com
Since the discovery of archaeoplankton in 1992, the euryarchaeotal Marine Group II (MGII)
remains uncultured and less understood than other planktonic archaea. We characterized the …

Attention-gated networks for improving ultrasound scan plane detection

J Schlemper, O Oktay, L Chen, J Matthew… - arXiv preprint arXiv …, 2018 - arxiv.org
In this work, we apply an attention-gated network to real-time automated scan plane detection
for fetal ultrasound screening. Scan plane detection in fetal ultrasound is a challenging …