User profiles for Caroline Johnston
 | Caroline JohnstonKing's College London Verified email at niwa.co.nz Cited by 3355 |
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
AJ Ridley, HF Paterson, CL Johnston, D Diekmann… - Cell, 1992 - cell.com
The function of rat, a ras-related GTP-binding protein, was investigated in fibroblasts by
microinjection. In confluent serum-starved Swiss 3T3 cells, racl rapidly stimulated actin filament …
microinjection. In confluent serum-starved Swiss 3T3 cells, racl rapidly stimulated actin filament …
[HTML][HTML] The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
…, KS Hwang, CR Jack, M Jenkinson, C Johnston… - Brain imaging and …, 2014 - Springer
The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a
collaborative network of researchers working together on a range of large-scale studies that …
collaborative network of researchers working together on a range of large-scale studies that …
Interaction of Rac with p67phox and Regulation pf Phagocytic NADPH Oxidase Activity
D Diekmann, A Abo, C Johnston, AW Segal, A Hall - Science, 1994 - science.org
Rho and Rac, two members of the Ras superfamily of guanosine triphosphate (GTP)-binding
proteins, regulate a variety of signal transduction pathways in eukaryotic cells. Upon …
proteins, regulate a variety of signal transduction pathways in eukaryotic cells. Upon …
T-cell infiltration and signaling in the adult dorsal spinal cord is a major contributor to neuropathic pain-like hypersensitivity
…, A Moss, A Latremoliere, C Johnston… - Journal of …, 2009 - Soc Neuroscience
Partial peripheral nerve injury in adult rats results in neuropathic pain-like hypersensitivity,
while that in neonatal rats does not, a phenomenon also observed in humans. We therefore …
while that in neonatal rats does not, a phenomenon also observed in humans. We therefore …
A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets
…, V Ramesh, E Pacary, C Johnston… - Genes & …, 2011 - genesdev.cshlp.org
Proneural genes such as Ascl1 are known to promote cell cycle exit and neuronal differentiation
when expressed in neural progenitor cells. The mechanisms by which proneural genes …
when expressed in neural progenitor cells. The mechanisms by which proneural genes …
The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis
The CATH database of protein domain structures ( http://www.biochem.ucl.ac.uk/bsm/cath/ )
currently contains 43 229 domains classified into 1467 superfamilies and 5107 sequence …
currently contains 43 229 domains classified into 1467 superfamilies and 5107 sequence …
[HTML][HTML] Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology
…, P Proitsi, S Nelson, S Williams, C Johnston… - Alzheimer's & …, 2014 - Elsevier
Blood proteins and their complexes have become the focus of a great deal of interest in the
context of their potential as biomarkers of Alzheimer's disease (AD). We used a SOMAscan …
context of their potential as biomarkers of Alzheimer's disease (AD). We used a SOMAscan …
Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study
…, S Williams, A Hodges, C Johnston… - Journal of …, 2014 - content.iospress.com
A blood-based protein biomarker, or set of protein biomarkers, that could predict onset and
progression of Alzheimer’s disease (AD) would have great utility; potentially clinically, but …
progression of Alzheimer’s disease (AD) would have great utility; potentially clinically, but …
[PDF][PDF] Ascl1 coordinately regulates gene expression and the chromatin landscape during neurogenesis
…, FF Vasconcelos, D Drechsel, C Marie, C Johnston… - Cell reports, 2015 - cell.com
The proneural transcription factor Ascl1 coordinates gene expression in both proliferating
and differentiating progenitors along the neuronal lineage. Here, we used a cellular model of …
and differentiating progenitors along the neuronal lineage. Here, we used a cellular model of …
[PDF][PDF] Cell volume measurement using scanning ion conductance microscopy
YE Korchev, J Gorelik, EV Sviderskaya, CL Johnston… - Biophysical journal, 2000 - cell.com
We report a novel scanning ion conductance microscopy (SICM) technique for assessing
the volume of living cells, which allows quantitative, high-resolution characterization of …
the volume of living cells, which allows quantitative, high-resolution characterization of …