Background: Single‐dose antimicrobial prophylaxis for major surgery is widely accepted
principle; recommendations have been based on laboratory studies and numerous clinical …

Glomerular diseases remain the leading cause of chronic and end-stage kidney disease.
Significant advances in our understanding of human glomerular diseases have been enabled …

Among African immigrants in Melbourne, Victoria, Australia, we demonstrated lower geometric
mean vitamin D levels in immigrants with latent tuberculosis infection than in those with …

Nephrotic-range proteinuria is due to glomerular diseases characterized by podocyte injury.
Glucocorticoids are the standard of care for most forms of nephrotic syndrome. However, the …

Diabetic nephropathy (DN) is the leading cause of chronic kidney disease in the United States
and is a major cause of cardiovascular disease and death. DN develops insidiously over …

Rationale: Inflammation and oxidative stress are linked to the deleterious effects of cigarette
smoke in producing chronic obstructive pulmonary disease (COPD). Myeloperoxidase (MPO…

In the mammal, definitive hematopoietic stem cells (HSCs) are first derived from mesodermal
cells within a region of the embryonic para-aortic splanchnopleura known as the aorta-…

Studies have shown that certain cells of the glomerular tuft begin to express proteins
considered unique to other cell types upon injury. Little is known about the response of parietal …

Objectives Antimicrobial stewardship (AMS) programmes have been developed with the
intention of reducing inappropriate and unnecessary use of antimicrobials, while improving the …

Rationale: The potential role of statins in treating chronic obstructive pulmonary disease (COPD)
is controversial, and it is unclear what anatomic COPD lesions statins affect. Objectives: …