User profiles for Carrie L. Partch
Carrie PartchProfessor of Biochemistry, UC Santa Cruz Verified email at ucsc.edu Cited by 5816 |
Molecular architecture of the mammalian circadian clock
CL Partch, CB Green, JS Takahashi - Trends in cell biology, 2014 - cell.com
Circadian clocks coordinate physiology and behavior with the 24h solar day to provide
temporal homeostasis with the external environment. The molecular clocks that drive these …
temporal homeostasis with the external environment. The molecular clocks that drive these …
Analysis of protein stability and ligand interactions by thermal shift assay
K Huynh, CL Partch - Current protocols in protein science, 2015 - Wiley Online Library
Purification of recombinant proteins for biochemical assays and structural studies is time‐consuming
and presents inherent difficulties that depend on the optimization of protein stability. …
and presents inherent difficulties that depend on the optimization of protein stability. …
Antibacterial membrane attack by a pore-forming intestinal C-type lectin
…, H Zheng, MG Derebe, KM Callenberg, CL Partch… - Nature, 2014 - nature.com
Human body-surface epithelia coexist in close association with complex bacterial communities
and are protected by a variety of antibacterial proteins. C-type lectins of the RegIII family …
and are protected by a variety of antibacterial proteins. C-type lectins of the RegIII family …
Role of structural plasticity in signal transduction by the cryptochrome blue-light photoreceptor
Cryptochromes are blue-light photoreceptors that regulate a variety of responses such as
growth and circadian rhythms in organisms ranging from bacteria to humans. Cryptochromes …
growth and circadian rhythms in organisms ranging from bacteria to humans. Cryptochromes …
Structural basis of the day-night transition in a bacterial circadian clock
Circadian clocks are ubiquitous timing systems that induce rhythms of biological activities in
synchrony with night and day. In cyanobacteria, timing is generated by a posttranslational …
synchrony with night and day. In cyanobacteria, timing is generated by a posttranslational …
Cryptochrome 1 regulates the circadian clock through dynamic interactions with the BMAL1 C terminus
The molecular circadian clock in mammals is generated from transcriptional activation by
the bHLH-PAS transcription factor CLOCK–BMAL1 and subsequent repression by PERIOD …
the bHLH-PAS transcription factor CLOCK–BMAL1 and subsequent repression by PERIOD …
Molecular basis for peptidoglycan recognition by a bactericidal lectin
RE Lehotzky, CL Partch, S Mukherjee… - Proceedings of the …, 2010 - National Acad Sciences
RegIII proteins are secreted C-type lectins that kill Gram-positive bacteria and play a vital role
in antimicrobial protection of the mammalian gut. RegIII proteins bind their bacterial targets …
in antimicrobial protection of the mammalian gut. RegIII proteins bind their bacterial targets …
CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch
Multisite phosphorylation of the PERIOD 2 (PER2) protein is the key step that determines the
period of the mammalian circadian clock. Previous studies concluded that an unidentified …
period of the mammalian circadian clock. Previous studies concluded that an unidentified …
Crystal structure of cryptochrome 3 from Arabidopsis thaliana and its implications for photolyase activity
Cryptochromes use near-UV/blue light to regulate a variety of growth and adaptive process.
Recent biochemical studies demonstrate that the Cryptochrome-Drosophila, Arabidopsis, …
Recent biochemical studies demonstrate that the Cryptochrome-Drosophila, Arabidopsis, …
Photochemistry and photobiology of cryptochrome blue‐light photopigments: the search for a photocycle
CL Partch, A Sancar - Photochemistry and photobiology, 2005 - Wiley Online Library
Cryptochromes are flavoproteins that exhibit high sequence and structural similarity to the
light‐dependent DNA‐repair enzyme, photolyase. Cryptochromes have lost the ability to …
light‐dependent DNA‐repair enzyme, photolyase. Cryptochromes have lost the ability to …