Excitatory (glutamatergic) synapses in the mammalian brain are usually situated on dendritic
spines, a postsynaptic microcompartment that also harbors organelles involved in protein …

Dendritic spines are small actin-rich protrusions from neuronal dendrites that form the
postsynaptic part of most excitatory synapses and are major sites of information processing and …

Dendritic spines are the major sites of excitatory synaptic input, and their morphological
changes have been linked to learning and memory processes. Here, we report that growing …

Several microtubule binding proteins, including CLIP-170 (cytoplasmic linker protein-170),
CLIP-115, and EB1 (end-binding protein 1), have been shown to associate specifically with …

Hypertrophic scarring and poor intrinsic axon growth capacity constitute major obstacles for
spinal cord repair. These processes are tightly regulated by microtubule dynamics. Here, …

The molecular mechanisms that determine the size and complexity of the neuronal dendritic
tree are unclear. Here, we show that the phosphoinositide-3′ kinase (PI3K)–Akt–…

Microtubules are one of the major cytoskeletal components of neurons, essential for many
fundamental cellular and developmental processes, such as neuronal migration, polarity, and …

CLIP-170 and CLIP-115 are cytoplasmic linker proteins that associate specifically with the
ends of growing microtubules and may act as anti-catastrophe factors. Here, we have isolated …

The postsynaptic density (PSD) of central excitatory synapses is essential for postsynaptic
signaling, and its components are heterogeneous among different neuronal subtypes and …

The inferior olive, which provides the climbing fibers to Purkinje cells in the cerebellar cortex,
has been implicated in various functions, such as learning and timing of movements, and …