A reference map of the human binary protein interactome

…, C Colabella, G Coppin, C D'amata, D De Ridder… - Nature, 2020 - nature.com
Global insights into cellular organization and genome function require comprehensive
understanding of the interactome networks that mediate genotype–phenotype relationships 1 , 2 . …

[HTML][HTML] Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release

…, M Kitner, C Haeberli, J Pyche, C D'Amata… - Communications …, 2022 - nature.com
Nematode parasites of humans, livestock and crops dramatically impact human health and
welfare. Alarmingly, parasitic nematodes of animals have rapidly evolved resistance to …

[HTML][HTML] An optimized QF-binary expression system for use in zebrafish

…, R Sadhak, S Chiang, A Weiss, C D'Amata… - Developmental …, 2020 - Elsevier
The zebrafish model organism has been of exceptional utility for the study of vertebrate
development and disease through the application of tissue-specific labelling and overexpression …

A syngeneic spontaneous zebrafish model of tp53-deficient, EGFRviii, and PI3KCA H1047R-driven glioblastoma reveals inhibitory roles for inflammation during tumor …

A Weiss, C D'Amata, BJ Pearson, MN Hayes - bioRxiv, 2023 - biorxiv.org
To build a patient-relevant in vivo model of human glioblastoma, we expressed common
oncogenic variants including activated human EGFR viii and PI3KCA H1047R under the control …

Nementin is a Nematode-Selective Small Molecule Agonist of Neurotransmitter Release

…, A Au, M Kitner, C Haeberli, J Pyche, C D'Amata… - bioRxiv, 2022 - biorxiv.org
Nematode parasites of humans, livestock and crops pose a significant burden on human health
and welfare. Alarmingly, parasitic nematodes of animals have rapidly evolved resistance …

A human chimeric retinal organoid model for studying donor-host cell interactions in cell therapies of inherited retinal disease.

C D'Amata, K Ashworth, Z Baghestani… - … & Visual Science, 2023 - iovs.arvojournals.org
Purpose: There are no human models of cell engraftment to study allogeneic donor-host
cell interactions in a degenerating retina. We have generated chimeric retinal organoids (“…

Designing Chimeric Retinal Organoids as a Model for Stem Cell Engraftment in Inherited Retinal Disease

KE Ashworth, C D'Amata… - … & Visual Science, 2023 - iovs.arvojournals.org
Purpose: No pre-clinical model exists to examine human-to-human donor-host cell interaction
and engraftment in cell therapies for inherited retinal disease (IRD). We propose a novel …

[BOOK][B] Characterizing the Role of ice1 in Maintaining Zebrafish Neural Stem Cells

CM D'Amata - 2017 - search.proquest.com
Maintenance of neural stem cell (NSC) niches is required for the continued growth of the
zebrafish retina and forebrain after embryogenesis. The zebrafish mutant kes s564, which maps …

A Case Study of Indigenous Representation in Film Music: Smoke Signals and Dances with Wolves

SA D'Amata - 2020 - yorkspace.library.yorku.ca
… To my husband Peter and my sister Cassandra – words cannot express how appreciative I’ve
been for your love and … In this scene, the Coeur d’Alene protagonists are forced to relocate …

Toxicological profile for beryllium

C Smith, L Ingerman, R Amata - 2002 - stacks.cdc.gov
… 14 d 5dlwk 6hr/d … 10 d 5dlwk 6hrld … 15 d 5dlwk 6hr/d