Adenosine acts in parallel as a neuromodulator and as a homeostatic modulator in the central
nervous system. Its neuromodulatory role relies on a balanced activation of inhibitory A 1 …

Glycoconjugates constitute a major class of biomolecules which include glycoproteins,
glycosphingolipids and proteoglycans. Glycans are involved in several physiological and …

Cancer is a deadly disease that encompasses numerous cellular modifications. Among them,
alterations in glycosylation are a proven reliable hallmark of cancer, with most biomarkers …

Several phenolic acids caffeic and gallic acid derivatives were synthesized and screened for
their potential antiproliferative and cytotoxic properties, in different human cancer cell lines: …

A familial form of the neurodegenerative disease amyotrophic lateral sclerosis (ALS), is caused
by dominant mutations in the cytosolic Cu,Zn superoxide dismutase (SOD1). There has …

Background Brain-derived neurotrophic factor (BDNF) has been shown to control microglial
responses in neuropathic pain. Since adenosine A 2A receptors (A 2A Rs) control …

2. Methods This document represents the third version of the European Consensus on
reproduction in IBD. The development of this Consensus included the formulation of population, …

Tumour metastasis is the main cause of cancer related deaths. Metastasis is an intricate
multi-step process that requires the acquisition of several cancer cell features, including the …

Recent studies combining pharmacological, behavioral, electrophysiological and molecular
approaches indicate that depression results from maladaptive neuroplastic processes …

… Bennett2, Joana Gomes1, Ana Magalhaes1, Catarina Gomes1, Leonor David1,3, Imran
Dar2, Charlotte Jeanneau2, Shawn DeFrees4, Dorrit Krustrup5, Lotte K. Vogel2, Elin H …