Obesity is heritable and predisposes to many diseases. To understand the genetic basis of
obesity better, here we conduct a genome-wide association study and Metabochip meta-…

Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide
significance that together explained one-fifth of the heritability for adult height. By testing …

Background Misconceptions about ADHD stigmatize affected people, reduce credibility of
providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with …

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic
outcomes, independent of overall adiposity. To increase our understanding of the genetic …

High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease.
We report the largest genetic association study of blood pressure traits (systolic, diastolic …

Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …

Background Neuroimaging studies have shown structural alterations in several brain regions
in children and adults with attention deficit hyperactivity disorder (ADHD). Through the …

The highly complex structure of the human brain is strongly shaped by genetic influences 1 .
Subcortical brain regions form circuits with cortical areas to coordinate movement 2 , …

Attention-deficit/hyperactivity disorder (ADHD) is associated with functional impairments in
different areas of daily life. One such area is social functioning. The purpose of this paper is to …

Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are both
highly heritable neurodevelopmental disorders. Evidence indicates both disorders co-occur …