Intranasal inoculation of an MVA-based vaccine induces IgA and protects the respiratory tract of hACE2 mice from SARS-CoV-2 infection

JL Americo, CA Cotter, PL Earl… - Proceedings of the …, 2022 - National Acad Sciences
Current vaccines have greatly diminished the severity of the COVID-19 pandemic, even though
they do not entirely prevent infection and transmission, likely due to insufficient immunity …

One or two injections of MVA-vectored vaccine shields hACE2 transgenic mice from SARS-CoV-2 upper and lower respiratory tract infection

R Liu, JL Americo, CA Cotter, PL Earl… - Proceedings of the …, 2021 - National Acad Sciences
Modified vaccinia virus Ankara (MVA) is a replication-restricted smallpox vaccine, and
numerous clinical studies of recombinant MVAs (rMVAs) as vectors for prevention of other …

Preparation of cell cultures and vaccinia virus stocks

CA Cotter, PL Earl, LS Wyatt… - Current Protocols in …, 2017 - Wiley Online Library
The culturing of cell lines used with vaccinia virus, both as monolayer and in suspension, is
described. The preparation of chick embryo fibroblasts (CEF) is presented for use in the …

Elucidating and minimizing the loss by recombinant vaccinia virus of human immunodeficiency virus gene expression resulting from spontaneous mutations and …

…, PL Earl, W Xiao, JL Americo, CA Cotter… - Journal of …, 2009 - Am Soc Microbiol
While characterizing modified vaccinia virus recombinants (rMVAs) containing human
immunodeficiency virus env and gag-pol genes, we detected nonexpressing mutants by …

Duration of etanercept treatment and reasons for discontinuation in a cohort of juvenile idiopathic arthritis patients

…, HE Foster, JE Davidson, KL Hyrich, CB Cotter… - …, 2011 - academic.oup.com
Objective. Since 2004, juvenile idiopathic arthritis (JIA) patients treated with etanercept and/or
MTX have been monitored in the British Society for Paediatric and Adolescent …

[HTML][HTML] Inhibition of vaccinia virus L1 N-myristoylation by the host N-myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry

…, M Faronato, K Wilkins, CS Goldsmith, CA Cotter… - PLoS …, 2022 - journals.plos.org
We have recently shown that the replication of rhinovirus, poliovirus and foot-and-mouth
disease virus requires the co-translational N-myristoylation of viral proteins by human host cell N…

[BOOK][B] Canadian law dictionary

SG Coughlan, JA Yogis, CA Cotter - 2013 - digitalcommons.schulichlaw.dal.ca
Updated and expanded to reflect the most recent developments and revisions in Canadian
national and provincial law, this book is a concise guide to legal citation in Canada. Legal …

[HTML][HTML] Comparative live bioluminescence imaging of monkeypox virus dissemination in a wild-derived inbred mouse (Mus musculus castaneus) and outbred African …

PL Earl, JL Americo, CA Cotter, B Moss - Virology, 2015 - Elsevier
Monkeypox virus belongs to the orthopoxvirus genus, infects rodents and monkeys in Africa,
produces a smallpox-like zoonotic disease in humans, and has the potential for global …

Comparison of the immunogenicity and protective efficacy of ACAM2000, MVA, and vectored subunit vaccines for Mpox in rhesus macaques

…, K McMahan, J Liu, OC Powers, CA Cotter… - Science Translational …, 2024 - science.org
The 2022–2023 mpox outbreak triggered vaccination efforts using smallpox vaccines that
were approved for mpox, including modified vaccinia Ankara (MVA; JYNNEOS), which is a …

[HTML][HTML] Protection from SARS-CoV-2 Variants by MVAs expressing matched or mismatched S administered intranasally to mice

CA Cotter, JL Americo, PL Earl, B Moss - npj Vaccines, 2023 - nature.com
SARS-CoV-2 vaccines prevent severe disease but are less efficient in averting infection and
transmission of variant strains, making it imperative to explore ways of enhancing protection…