Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3, randomised …

…, C Cazanave, C Chabartier, C Chirouze… - The Lancet infectious …, 2022 - thelancet.com
Background The antiviral efficacy of remdesivir against SARS-CoV-2 is still controversial.
We aimed to evaluate the clinical efficacy of remdesivir plus standard of care compared with …

Preeminence of Staphylococcus aureus in Infective Endocarditis: A 1-Year Population-Based Survey

…, T Doco-Lecompte, C Chirouze… - Clinical infectious …, 2012 - academic.oup.com
Background. Observational studies showed that the profile of infective endocarditis (IE)
significantly changed over the past decades. However, most studies involved referral centers. We …

Temporal trends in infective endocarditis in the context of prophylaxis guideline modifications: three successive population-based surveys

…, M Celard, C Poyart, C Strady, C Chirouze… - Journal of the American …, 2012 - jacc.org
Objectives : The goal of this study was to evaluate temporal trends in infective endocarditis (IE)
incidence and clinical characteristics after 2002 French IE prophylaxis guideline …

Antibiotic treatment for 6 weeks versus 12 weeks in patients with pyogenic vertebral osteomyelitis: an open-label, non-inferiority, randomised, controlled trial

…, A Therby, D Bouhour, E Dénes, A Debard, C Chirouze… - The Lancet, 2015 - thelancet.com
Background Duration of treatment for patients with vertebral osteomyelitis is mainly based
on expert recommendation rather than evidence. We aimed to establish whether 6 weeks of …

[HTML][HTML] High prevalence of SARS-CoV-2 antibodies in pets from COVID-19+ households

…, J Vanhomwegen, MA Gouilh, A Kodjo, C Chirouze… - One Health, 2020 - Elsevier
In a survey of household cats and dogs of laboratory-confirmed COVID-19 patients, we found
a high seroprevalence of SARS-CoV-2 antibodies, ranging from 21% to 53%, depending …

Non-HACEK gram-negative bacillus endocarditis

…, D Iarussi, J Klein, C Chirouze… - Annals of internal …, 2007 - acpjournals.org
Background: Infective endocarditis caused by non-HACEK (species other than Haemophilus
species, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella …

Low serum procalcitonin level accurately predicts the absence of bacteremia in adult patients with acute fever

C Chirouze, H Schuhmacher, C Rabaud… - Clinical infectious …, 2002 - academic.oup.com
The ability of measurement of serum procalcitonin (PCT) levels to differentiate bacteremic
from nonbacteremic infectious episodes in patients hospitalized for community-acquired …

Elevated D-dimers and lack of anticoagulation predict PE in severe COVID-19 patients

…, G Mourey, Q Lepiller, C Chirouze… - European …, 2020 - Eur Respiratory Soc
Background Coronavirus disease 2019 (COVID-19) may predispose to venous
thromboembolism. We determined factors independently associated with computed tomography …

Antibiotic therapy for 6 or 12 weeks for prosthetic joint infection

…, JM Laffosse, T Begué, C Chirouze… - … England Journal of …, 2021 - Mass Medical Soc
Background The management of prosthetic joint infection usually consists of a combination
of surgery and antimicrobial therapy. The appropriate duration of antimicrobial therapy for …

Impact of Early Valve Surgery on Outcome of Staphylococcus aureus Prosthetic Valve Infective Endocarditis: Analysis in the International Collaboration of …

C Chirouze, F Alla, VG Fowler Jr… - Clinical Infectious …, 2015 - academic.oup.com
Background. The impact of early valve surgery (EVS) on the outcome of Staphylococcus
aureus (SA) prosthetic valve infective endocarditis (PVIE) is unresolved. The objective of this …