[HTML][HTML] Blood DNA methylation and COVID-19 outcomes

…, A Tiwari, CE Vincent, A Chopra, PA Vincent… - Clinical …, 2021 - Springer
Background There are no prior reports that compare differentially methylated regions of
DNA in blood samples from COVID-19 patients to samples collected before the SARS-CoV-2 …

Defining mitochondrial protein functions through deep multiomic profiling

…, KA Overmyer, AZ Salome, AS Hebert, CE Vincent… - Nature, 2022 - nature.com
Mitochondria are epicentres of eukaryotic metabolism and bioenergetics. Pioneering efforts
in recent decades have established the core protein componentry of these organelles 1 and …

Mass spectrometry proteomics reveals a function for mammalian CALCOCO1 in MTOR-regulated selective autophagy

…, AM Davis, ND Lowry, CE Vincent, E Shishkova… - Autophagy, 2020 - Taylor & Francis
Macroautophagy/autophagy is suppressed by MTOR (mechanistic target of rapamycin kinase)
and is an anticancer target under active investigation. Yet, MTOR-regulated autophagy …

Deaccelerated myogenesis and autophagy in genetically induced pulmonary emphysema

J Balnis, LA Drake, DV Singer, CE Vincent… - American Journal of …, 2022 - atsjournals.org
Patients with chronic obstructive pulmonary disease (COPD)–pulmonary emphysema often
develop locomotor muscle dysfunction, which entails reduced muscle mass and force-…

High CO2 Downregulates Skeletal Muscle Protein Anabolism via AMP-activated Protein Kinase α2–mediated Depressed Ribosomal Biogenesis

TC Korponay, J Balnis, CE Vincent… - American Journal of …, 2020 - atsjournals.org
High CO 2 retention, or hypercapnia, is associated with worse outcomes in patients with
chronic pulmonary diseases. Skeletal muscle wasting is also an independent predictor of poor …

IL-13-driven pulmonary emphysema leads to skeletal muscle dysfunction attenuated by endurance exercise

J Balnis, TC Korponay, CE Vincent… - Journal of Applied …, 2020 - journals.physiology.org
Patients with chronic obstructive pulmonary disease (COPD) usually develop skeletal
muscle dysfunction, which represents a major comorbidity in these patients and is strongly …

SDH subunit C regulates muscle oxygen consumption and fatigability in an animal model of pulmonary emphysema

J Balnis, LA Drake, CE Vincent… - American Journal of …, 2021 - atsjournals.org
Patients with pulmonary emphysema often develop locomotor muscle dysfunction, which is
independently associated with disability and higher mortality in that population. Muscle …

[PDF][PDF] Thermoeconomic analysis & design of domestic refrigeration systems

CE Vincent, MK Heun - Domestic use of energy conference, 2006 - Citeseer
Domestic refrigeration consumes a significant percentage of total energy used in both South
Africa and the United States. This paper explores and optimizes the thermoeconomics of the …

[HTML][HTML] Neutron-encoded signatures enable product ion annotation from tandem mass spectra

AL Richards, CE Vincent, A Guthals, CM Rose… - Molecular & Cellular …, 2013 - ASBMB
We report the use of neutron-encoded (NeuCode) stable isotope labeling of amino acids in
cell culture for the purpose of C-terminal product ion annotation. Two NeuCode labeling …

[HTML][HTML] Established biomarkers of chronic obstructive pulmonary disease reflect skeletal muscle integrity's response to exercise in an animal model of pulmonary …

J Balnis, CE Vincent, AJ Jones, LA Drake… - American Journal of …, 2020 - atsjournals.org
Methods Experiments were conducted using CC10-rtTA-IL-13 (IL13 TG) doxycycline-inducible
transgenic mice that develop chronic lung remodeling reminiscent of pulmonary …