[HTML][HTML] Characterization of urine stem cell-derived extracellular vesicles reveals B cell stimulating cargo

…, GB Perkins, GM Mourad, CJM Stapledon… - International journal of …, 2021 - mdpi.com
Elucidation of the biological functions of extracellular vesicles (EVs) and their potential roles
in physiological and pathological processes is an expanding field of research. In this study, …

[HTML][HTML] Human osteocyte expression of Nerve Growth Factor: The effect of Pentosan Polysulphate Sodium (PPS) and implications for pain associated with knee …

CJM Stapledon, H Tsangari, LB Solomon… - PloS one, 2019 - journals.plos.org
Pentosan polysulphate sodium (PPS) is a promising therapeutic agent for blocking knee
pain in individuals with knee osteoarthritis (KOA). The mode of action of PPS in this context is …

[HTML][HTML] Anti-inflammatory actions of Pentosan polysulfate sodium in a mouse model of influenza virus A/PR8/34-induced pulmonary inflammation

R Krishnan, CJM Stapledon, H Mostafavi… - Frontiers in …, 2023 - frontiersin.org
Introduction There is an unmet medical need for effective anti-inflammatory agents for the
treatment of acute and post-acute lung inflammation caused by respiratory viruses. The semi-…

Relationships between the bone expression of Alzheimer's disease-related genes, bone remodelling genes and cortical bone structure in neck of femur fracture

CJM Stapledon, R Stamenkov, R Cappai… - Calcified Tissue …, 2021 - Springer
Neck of femur (NOF) fracture is a prevalent fracture type amongst the ageing and osteoporotic
populations, commonly requiring total hip replacement (THR) surgery. Increased fracture …

Both ligand and VDR expression levels critically determine the effect of 1α, 25-dihydroxyvitamin-D3 on osteoblast differentiation

…, KR Barratt, R Triliana, CJM Stapledon… - The Journal of Steroid …, 2018 - Elsevier
Previous studies have shown that 1α,25-dihydroxyvitamin D 3 (1,25D) through vitamin D
receptor (VDR) signalling has both catabolic and anabolic effects on osteoblast differentiation. …

[HTML][HTML] Pentosan polysulfate sodium prevents functional decline in chikungunya infected mice by modulating growth factor signalling and lymphocyte activation

PA Rudd, EXY Lim, CJM Stapledon, R Krishnan… - Plos one, 2021 - journals.plos.org
Chikungunya virus (CHIKV) is an arthropod-borne virus that causes large outbreaks world-wide
leaving millions of people with severe and debilitating arthritis. Interestingly, clinical …

A Novel Investigation into the Role of Neurotrophic Factors in the Osteocyte and Bone

CJM Stapledon - 2020 - digital.library.adelaide.edu.au
… I, Catherine Stapledon ce1iify that this work contains no material which has been accepted
for the award of any other degree or diploma in my name in any university or other te1iiary …

Cognitive decline is associated with an accelerated rate of bone loss and increased fracture risk in women: a prospective study from the Canadian Multicentre …

…, TV Nguyen, LB Solomon, C Stapledon… - Journal of Bone and …, 2021 - academic.oup.com
Cognitive decline and osteoporosis often coexist and some evidence suggests a causal link.
However, there are no data on the longitudinal relationship between cognitive decline, …

[PDF][PDF] Both ligand and VDR expression levels critically determine the effect of 1α, 25

…, KR Barratt, R Triliana, CJM Stapledon… - 2017 - academia.edu
… Barratt, Rahma Triliana, Catherine JM Stapledon, Hong Zhou, David M. Findlay, Howard
A. Morris, Gerald J. … Barratt, Rahma Triliana, Catherine JMStapledon, Hong Zhou, David M.Findlay …

Both ligand and VDR expression levels critically determine the effect of 1α, 25-dihydroxyvitamin-D₃ on osteoblast differentiation

…, A Wijenayaka, K Barratt, R Triliana, C Stapledon… - 2018 - hekyll.services.adelaide.edu.au
Adelaide Research & Scholarship: Both ligand and VDR expression levels critically determine
the effect of 1α,25-dihydroxyvitamin-D₃ on osteoblast differentiation Skip navigation …