Natural killer (NK) cells play critical roles in innate immunity and in bridging innate and
adaptive immune responses against viral infection. However, the response of NK cells to …

In high-transmission regions, we expect parasite lineages within complex malaria infections
to be unrelated due to parasite inoculations from different mosquitoes. This project was …

Monkeypox virus (MPXV) infection has recently expanded in geographic distribution and
can be fatal in up to 10% of cases. The intravenous (iv) inoculation of nonhuman primates (…

Nipah virus (NiV) is a paramyxovirus (genus Henipavirus) that emerged in the late 1990s in
Malaysia and has since been identified as the cause of sporadic outbreaks of severe febrile …

Background: Endothelial dysfunction signals the initiation and progression of atherosclerosis.
Elevated LDL-cholesterol concentrations have been suggested to induce endothelial …

Genetic crosses are most powerful for linkage analysis when progeny numbers are high,
parental alleles segregate evenly and numbers of inbred progeny are minimized. We …

Population genomics of bulk malaria infections is unable to examine intrahost evolution;
therefore, most work has focused on the role of recombination in generating genetic variation. …

Infection of non-human primates (NHPs) such as rhesus and cynomolgus macaques with
monkeypox virus (MPXV) or cowpox virus (CPXV) serve as models to study poxvirus …

Simian Hemorrhagic Fever Virus (SHFV) has caused sporadic outbreaks of hemorrhagic
fevers in macaques at primate research facilities. SHFV is a BSL-2 pathogen that has not been …

THE first step in infection by the human immunodeficiency virus (HIV) is the specific binding
of gp!20, the envelope glycoprotein of HIV, to its cellular receptor, CD4 (see ref. 1 for review). …