Synthesis of septal peptidoglycan (sPG) is crucial for bacterial cell division. FtsW, an indispensable
component of the cell division machinery in all walled bacterial species, was recently …

Helical cell shape is necessary for efficient stomach colonization by Helicobacter pylori, but
the molecular mechanisms for generating helical shape remain unclear. The helical …

Bacterial cells are surrounded by a polymer known as peptidoglycan (PG), which protects
the cell from changes in osmotic pressure and small molecule insults. A component of this …

Uridine diphosphate N-acetyl muramic acid (UDP NAM) is a critical intermediate in bacterial
peptidoglycan (PG) biosynthesis. As the primary source of muramic acid that shapes the PG …

The human innate immune system responds to both pathogen and commensal bacteria at
the molecular level using bacterial peptidoglycan (PG) recognition elements. Traditionally, …

The oral microbiome is critical to human health and disease, yet the role that host salivary
proteins play in maintaining oral health is unclear. A highly expressed gene in human salivary …

Bacteria surround themselves with cell walls to maintain cell rigidity and protect against
environmental insults. Here we review chemical and biochemical techniques employed to study …

Bacterial peptidoglycan (PG) is recognized by the human innate immune system to generate
an appropriate response. To gain an appreciation of how this essential polymer is sensed, …

… She is currently pursuing her PhD with Catherine L. Grimes at University of Delaware. …
Catherine Grimes at the University of Delaware, studying the role of the bacterial-derived …

Bacteria have the natural ability to install protective postsynthetic modifications onto its
bacterial peptidoglycan (PG), the coat woven into bacterial cell wall. Peptidoglycan O-…