Scientists visualize data for a range of purposes, from exploring unfamiliar data sets to
communicating insights revealed by visual analyses. As the supply of numerical environmental …

Clear cell renal cell carcinoma (ccRCC) is characterized by inactivation of the von Hippel-Lindau
tumour suppressor gene (VHL) 1 , 2 . Because no other gene is mutated as frequently …

A key goal of whole-genome sequencing for studies of human genetics is to interrogate all
forms of variation, including single-nucleotide variants, small insertion or deletion (indel) …

Identifying large expansions of short tandem repeats (STRs), such as those that cause
amyotrophic lateral sclerosis (ALS) and fragile X syndrome, is challenging for short-read whole-…

Genomic rearrangements are a hallmark of human cancers. Here, we identify the piggyBac
transposable element derived 5 (PGBD5) gene as encoding an active DNA transposase …

Autism arises in high and low-risk families. De novo mutation contributes to autism incidence
in low-risk families as there is a higher incidence in the affected of the simplex families than …

X-linked adrenoleukodystrophy (X-ALD) is a progressive peroxisomal disorder affecting
adrenal glands, testes and myelin stability that is caused by mutations in the ABCD1 (…

Less than half of individuals with a suspected Mendelian condition receive a precise molecular
diagnosis after comprehensive clinical genetic testing. Improvements in data quality and …

Geography and earth science educators are simultaneously faced with increasing scrutiny
of teaching, new educational standards and a plethora of new teaching methods such as …

This chapter discusses methods for displaying three or more geographically referenced
data variables. In particular, we are concerned with methods appropriate for exploratory …