Lymphatic vessels are lined by lymphatic endothelial cells (LECs), and are critical for health.
However, the role of metabolism in lymphatic development has not yet been elucidated. …

Tissue and vessel wall stiffening alters endothelial cell properties and contributes to vascular
dysfunction. However, whether extracellular matrix (ECM) stiffness impacts vascular …

Endothelial cells line blood and lymphatic vessels and form intercellular junctions, which
preserve vessel structure and integrity. The vascular endothelial cadherin, VE ‐cadherin, …

Rationale: Lymphatic vessel formation and function constitutes a physiologically and
pathophysiologically important process, but its genetic control is not well understood. Objective: …

BACKGROUND. Lack of investigatory and diagnostic tools has been a major contributing
factor to the failure to mechanistically understand lymphedema and other lymphatic disorders …

The liver is a major biosynthetic and detoxifying organ in vertebrates, but also generates 25-50%
of the lymph passing through the thoracic duct and is thereby the organ with the highest …

Like the circulatory blood vessel system, the dendriform lymphatic vascular system forms a
disseminated organ that is virtually indispensible for the function of most other organs. …

Detection, segmentation, and quantification of individual cell nuclei is a standard task in
biomedical applications. Due to the increasing volume of acquired image data, it is not possible …

The lymphatic system plays important roles in draining fluids from interstitial spaces,
absorbing lipids from the intestinal tract, and transporting white blood cells, including antigen-…

All animals with a blood vascular system also have a lymphatic vascular system. The lymphatic
vasculature is essential for maintaining fluid homeostasis, immune surveillance, and fat …